نتایج جستجو برای: reactogenicity
تعداد نتایج: 566 فیلتر نتایج به سال:
The rapid availability of effective vaccines against SARS-CoV-2 was key during the COVID-19 pandemic. However, vaccine hesitancy and relatively low coverage rates among general population particularly vulnerable populations such as healthcare staff reduced potential benefits these vaccines. During early phase pandemic, fear vaccine-related adverse events common individuals who refused vaccinati...
A tissue culture method using MDCK cells grown under serum-free conditions was developed to produce an inactivated influenza subunit vaccine. The first clinical data suggest it to be equal to the conventional egg-derived influenza subunit vaccine. In a double-blind controlled trial, 2 groups (n = 57 each) of adult volunteers were immunized with experimental bivalent influenza subunit vaccine de...
In countries where routine varicella vaccination is implemented, it is usually given at the same age as that recommended for measles-mumps-rubella (MMR) vaccination. A combined multivalent measles-mumps-rubella-varicella (MMRV) vaccine would offer the convenience of a single injection and facilitate implementation of varicella vaccination into routine childhood immunisation schedules. We evalua...
Introduction Phased distribution of the ChAdOx1nCoV-19 (Covisheild) vaccine was commenced in Sri Lanka January 2021. Although well tolerated with a low reactogenicity profile clinical trials, there were safety concerns shortly after initiating rollouts many countries. Objectives This prospective observational study aimed to adverse events following immunization (AEFI) amongst recipients between...
BACKGROUND We conducted a phase I, randomized, double-blind, placebo-controlled trial to assess the safety and immunogenicity of escalating doses of two recombinant replication defective adenovirus serotype 35 (Ad35) vectors containing gag, reverse transcriptase, integrase and nef (Ad35-GRIN) and env (Ad35-ENV), both derived from HIV-1 subtype A isolates. The trial enrolled 56 healthy HIV-uninf...
BACKGROUND Leprosy is an infectious disease caused by the bacterium Mycobacterium leprae. Influenza vaccine is an important influenza prevention strategy and the preparations used display good safety and tolerability profiles. But the safety of applying influenza vaccine on the clinical cured leprosy patients is unclear. METHODS We conducted an observational clinical study, in Wuhan between N...
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