[1] The value restored and added by dynamical downscaling is quantitatively evaluated by considering the spectral behavior of the Regional Atmospheric Modeling System (RAMS) in relation to its domain size and grid spacing. A regional climate model (RCM) simulation is compared with NCEP Reanalysis data regridded to the RAMS grid at each model analysis time for a set of six basic experiments. At ...

A product model is a formal and structured definition of product information. The most common procedure for defining a product data model is to first describe the business and/or engineering process in a formal process model, then to create a product data model based on the process model. However, there is a logical gap between process modeling and product modeling methods in the current ISO 10...

R EFLECTANCECONFOCALMICROSCOPY(RCM) represents a novel technique for the in vivo visualizationoftheskinatanearlyhistologic resolution. We investigated the possibility of detecting Sarcoptes scabiei using RCM. Three patients with lesions suggestive of scabies were examined by RCM. On confocal images, S scabiei appeared as an ovoid body with a dorsal surface marked by refractive bristles and spin...

In vivo reflectance confocal microscopy (RCM) constitutes a novel non-invasive imaging method that enables visualization of cells and structures in living skin in real time with resolution close to histological analysis. RCM has been successfully implemented in the assessment of benign and malignant lesions. It also enables monitoring dynamic changes in the skin over time and in response to dif...

Patients with photodermatoses or actinic keratosis benefit from very high ultraviolet B-ultraviolet A (UVB-UVA) photoprotection. However, poor compliance is an issue that jeopardizes adequate protection, leading to disease recurrence. This study evaluated the efficacy of a daily protective moisturizer with high UVB and UVA photoprotection applied 8 h before irradiation. A monocentric, open-labe...

Results A total of 401 patients with a history of hypersensitivity reaction to RCM and were premedicated at re-exposure to RCM. Male was 177 (44.1%) and mean age was 55.83¡3⁄411.92 years. Most common hypersensitivity symptom was urticaria (259, 64.6%), followed by itching (36.7%), rash (21.4%) and angioedema (13.2%). Hypotension was reported in 9 (2.2%) and syncope 5 (1.2%). Systemic steroid wa...

Reflectance confocal microscopy (RCM) is a modern, non-invasive diagnostic method that enables real-time imaging of epidermis and upper layers of the dermis with a nearly histological precision and high contrast. The application of this technology in skin imaging in the last few years has resulted in the progress of dermatological diagnosis, providing virtual access to the living skin erasing t...

BACKGROUND Melanosis is the most common cause of mucosal pigmentation and can be clinically difficult to differentiate from early melanoma (MM). Dermoscopy can help in the distinction between melanosis and MM, but in some instances, melanoses may exhibit overlapping features with MM such as the presence of grey colour. OBJECTIVE We sought to evaluate whether reflectance confocal microscopy (R...

The cochlear microphonic (CM) is created primarily by the receptor currents of outer hair cells (OHCs) and may therefore be useful for identifying cochlear regions with impaired OHCs. However, the CM measured across the frequency range with round-window or ear-canal electrodes lacks place-specificity as it is dominated by cellular sources located most proximal to the recording site (e.g., at th...