BACKGROUND RC-101 is a congener of the antiretroviral peptide retrocyclin, which we and others have reported is active against clinical HIV-1 isolates from all major clades, does not hemagglutinate, and is non-toxic and non-inflammatory in cervicovaginal cell culture. Herein, film-formulated RC-101 was assessed for its antiviral activity in vitro, safety in vivo, retention in the cervix and vag...

Mid-story pin column system has been proposed to realize beam yielding mechanism of a steel moment-resisting frame. In this system, connection is applied inbetween the upper and lower RC extended from base control moment demands on both ends first story column. An exposed-type adopted as connected by single anchor bolt. Static cyclic horizontal loading tests partial frame consisting second floo...

According to current design practices of steel moment-resisting frames, formation plastic hinges is unavoidable when the frames are supported by conventional column base systems, i.e., exposed-type and embedded-type due unequalized flexural moment demand on top first story columns [1]. Kimura et.al [3] has proposed mid-story pin system avoid from yielding realize beam-yielding mechanism applyin...

We show the following results for polynomial-time reducibility to RC, the set of Kolmogorov random strings. 1. If P 6= NP, then SAT does not dtt-reduce to RC. 2. If PH does not collapse, then SAT does not n--reduce to RC for any α < 1. 3. If PH does not collapse, then SAT does not n-T-reduce to RC for any α < 2 . 4. There is a problem in E that does not dtt-reduce to RC. 5. There is a problem i...

Levi nondegenerate real-analytic hypersurfaces M ⊂ ƒ are well understood due to the seminal results of Tanaka [17] and Chern-Moser[5], where a complete set of local invariants for M has been defined. At the other extreme are those hypersurfaces which are locally CR-equivalent to a product M ׃, (take the real hyperplanes inƒ as a simple example). In-between there is a huge and much less underst...

Factors which hypothetically inl1uence r:t tes , vol umes, and methods of income generation in crack d istribution, USL~, a nd misuse a rc ind icatl'd, and a research program to investi gate them is suggL:stt:d. This research will contribuk signtficantly to the dc vc loprm:nt o f a theoretical fralllc\Vork which adL:quatcly rel:ttes Stibst;tncc using/abusing and trafficking populations to the w...

In this paper we have put forward an analytical model, which could accurately capture the on chip interconnect delay. As we move onto higher frequency range, of the order of GHz, the effects of shunt conductance cannot be ignored, as it provides a measure of the possible leakage. Due to this reason, we have derived our on-chip interconnect delay metric considering distributed RLCG segments, rat...

In moment resisting reinforced concrete framed buildings, corner joints are found at the roof level. These joints, if designed for gravity loads and are based on pre-seismic codes, may suffer substantial damage during earthquakes particularly under opening cycles, i.e. those causing flexural tension on the inside of the joint. Several techniques of repair and strengthening of reinforced concret...

RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation. However, its protective effect on lungs submitted to lung ischemia-reperfusion injury has not been addressed before. Then, we administrated RC-3095 intravenously before and after lung reperfusion using an animal model of lung ischemia-reperfusion injury (LIRI) by clampi...

It is an effective way to improve the flexural behavior of reinforced concrete (RC) members by externally bonded carbon fiber reinforcement polymer (CFRP) laminates on the soffit of the members. However, there is little investigation on flexural performance of RC beam flexurally strengthened by side-bonded FRP laminates. To investigate the flexural behavior of RC beams side-bonded CFRP laminate...