نتایج جستجو برای: rc

تعداد نتایج: 13540  

2012
Chaogang Shao Xiaoxia Ma Xiufang Xu Huizhong Wang Yijun Meng

MicroRNAs (miRNAs) are ∼21-nucleotide small RNAs (sRNAs) with essential regulatory roles in plants. They are generated from stem-loop-structured precursors through two sequential Dicer-like 1 (DCL1)-mediated cleavages. To date, hundreds of plant miRNAs have been uncovered. However, the question, whether the sequences reverse complementary (RC) to the miRNA precursors could form hairpin-like str...

2014
Anne Grünewald Nichola Z. Lax Mariana C. Rocha Amy K. Reeve Philippa D. Hepplewhite Karolina A. Rygiel Robert W. Taylor Doug M. Turnbull

BACKGROUND Respiratory chain (RC) deficiencies are found in primary mtDNA diseases. Focal RC defects are also associated with ageing and neurodegenerative disorders, e.g. in substantia nigra (SN) neurons from Parkinson's disease patients. In mitochondrial disease and ageing, mtDNA mutational loads vary considerably between neurons necessitating single cell-based assessment of RC deficiencies. E...

2013
Matthew P. Wood Amy L. Cole Piotr Ruchala Alan J. Waring Lisa C. Rohan Preston Marx Patrick M. Tarwater Phalguni Gupta Alexander M. Cole

Fusion inhibitors are a class of antiretroviral drugs used to prevent entry of HIV into host cells. Many of the fusion inhibitors being developed, including the drug enfuvirtide, are peptides designed to competitively inhibit the viral fusion protein gp41. With the emergence of drug resistance, there is an increased need for effective and unique alternatives within this class of antivirals. One...

Journal: :Gaceta sanitaria 2010
Nayara Mota Rosa Alvarez-Gil Montserrat Corral Socorro Rodríguez Holguín María Parada Alberto Crego Francisco Caamaño-Isorna Fernando Cadaveira

OBJECTIVE To evaluate the incidence of risky consumption (RC) and heavy episodic drinking (HED) in the Cohort of Spanish university students at two-year follow-up and to identify predictors of these patterns of alcohol consumption and the association between these patterns and academic achievement. METHOD We carried out a cohort study. Alcohol consumption was measured with the AUDIT. The foll...

2016
Yongxia Cui Beng Kah Song Lin-Feng Li Ya-Ling Li Zhongyun Huang Ana L Caicedo Yulin Jia Kenneth M Olsen

Weedy rice is a conspecific form of cultivated rice (Oryza sativa L.) that infests rice fields and results in severe crop losses. Weed strains in different world regions appear to have originated multiple times from different domesticated and/or wild rice progenitors. In the case of Malaysian weedy rice, a multiple-origin model has been proposed based on neutral markers and analyses of domestic...

2016
Jeremy W. Martin Estrella M. Carballido Ahmed Ahmed Bilal Farhan Rahul Dutta Cody Smith Ramy F. Youssef

OBJECTIVE To highlight the current understanding of the epidemiology, clinicopathological characteristics, and management of squamous cell carcinoma (SCC) of the bladder, as it accounts for 2-5% of bladder tumours, with a focus on non-bilharzial-associated SCC (NB-SCC). The standard treatment for bladder SCC remains radical cystectomy (RC). We present an updated clinical profile of bladder SCC ...

2014
Jan P. Kamiński Ajit Pai Luay Ailabouni John J. Park Slawomir J. Marecik Leela M. Prasad Herand Abcarian

BACKGROUND AND OBJECTIVES Limited data are available comparing epidural and patient-controlled analgesia in site-specific colorectal surgery. The aim of this study was to evaluate 2 modes of analgesia in patients undergoing laparoscopic right colectomy (RC) and low anterior resection (LAR). METHODS Prospectively collected data on 433 patients undergoing laparoscopic or laparoscopic-assisted c...

Journal: :The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2006
F Arnold A LaJoie T Marrie P Rossi F Blasi C Luna P Fernandez J Porras K Weiss C Feldman E Rodríguez G Levy F Arteta J Roig J Rello J Ramirez

SETTING A total of 33 hospitals in 13 countries in North America, Europe, Africa, Asia and Latin America. OBJECTIVE To investigate the relationship between the pneumonia severity index (PSI) and the time to clinical stability from intravenous to oral antibiotic therapy in hospitalized adult patients with community-acquired pneumonia (CAP). DESIGN An international, retrospective, observation...

2016
Hee Gyung Kang Hyun Kyung Lee Yo Han Ahn Je-Gun Joung Jaeyong Nam Nayoung K D Kim Jung Min Ko Min Hyun Cho Jae Il Shin Joon Kim Hye Won Park Young Seo Park Il-Soo Ha Woo Yeong Chung Dae-Yeol Lee Su Young Kim Woong Yang Park Hae Il Cheong

Nephronophthisis-related ciliopathy (NPHP-RC) is a common genetic cause of end-stage renal failure during childhood and adolescence and exhibits an autosomal recessive pattern of inheritance. Genetic diagnosis is quite limited owing to genetic heterogeneity in NPHP-RC. We designed a novel approach involving the step-wise screening of Sanger sequencing and targeted exome sequencing for the genet...

2015
Kee Jae Song Young-June Shin Kang Ro Lee Eun Jung Lee Yun Suk Suh Kyung-Su Kim

PURPOSE This study aims to investigate the additive effect of the Hedera helix (HH) and Rhizoma coptidis (RC) extracts mixture on antitussive and expectorant activities in animals. MATERIALS AND METHODS The expectorant assay was performed with phenol red secretion in mice trachea. Mice or guinea pigs were randomly divided into groups of 8 each, including negative and positive control groups. ...

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