Author Contribution: Ran Klein – Study design, methods implementation, data analysis, primary author Jennifer M. Renaud – Major contributions to methodology and secondary author Maria C. Ziadi – Operator 2 Stephanie L. Thorn – Operator 1 Andy Adler – Co-supervisor for Ran Klein, revising of manuscript Robert S. Beanlands – Head of Cardiac PET Centre producing data and patient recruitment, final...

In order to support communication and computation cooperation, we propose MC-RAN architecture, which consists of mobile cloud (MC) as the computation provision platform and radio access network (RAN) as the communication interface. The MC-RAN aims to undertake the following tasks: (1) to increase user equipments’ computing capacity by triggering offloading action, especially for those UEs which...

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are the two common neurodegenerative diseases that have been associated with the GGGGCC·GGCCCC repeat RNA expansion in a noncoding region of C9orf72. It has been previously reported that unconventional repeat-associated non-ATG (RAN) translation of GGGGCC·GGCCCC repeats produces five types of dipeptide-repeat proteins (referr...

Assembly and disassembly of the mitotic spindle are essential for both chromosome segregation and cell division. The small G-protein Ran has emerged as an important regulator of spindle assembly. In this review, we look at the role of Ran in different aspects of spindle assembly, including its effects on microtubule assembly dynamics and microtubule organization. In addition, we examine the pos...