نتایج جستجو برای: radiosensitizer
تعداد نتایج: 575 فیلتر نتایج به سال:
AT cells are extremely sensitive to ionizing radiation. Since the AT gene has homology to phosphatidylinositol 3 kinases(P13-kinases),wortman nm,a specificinhibitorofPI 3-kinase,wasusedtodetermineif P13-kinase activity regulates radiation sensitivity. Human and murine cells exposed to wortmannin alonedid not display significant cytotoxicity. Wortmanmn in combination with radiation was an effect...
Gemcitabine is the only chemotherapeutic agent approved by the U.S. Food and Drug Administration (FDA) for the treatment of advanced pancreatic cancer. 5-fluorouracil or its oral pro-drug, capecitabine is the second most commonly used agent in this malignancy. Capecitabine or 5-fluorouracil is the second most common agent used either in second-line or as a radiosensitizer. Thromboembolism requi...
The bioregulatory molecule, nitric oxide (NO), was evaluated as a liypoxic cell radiosensitizer. Authentic NO gas was nearly as effective as oxygen in radiosensitizing hypoxic Chinese hamster V79 lung cells as evaluated using clonogenic assays. When NO was delivered to hypoxic Chinese hamster V79 cells using the NO-releasing agent i( ',lls),N[N(())NO| NV, radiosensitization was also observed wi...
Extraskeletal Ewing's sarcoma is a rare soft tissue tumor that is morphologically indistinguishable from Ewing's sarcoma of bone. We report a case of extraskeletal Ewing's sarcoma with several systemic problems. A 69-year-old man presented with a 5-month history of a rapidly enlarging mass in the right thigh. Because preoperative radiotherapy with sanazole (AK-2123) contributed the tumor mass r...
Although a relatively uncommon disease, pancreatic adenocarcinoma has had a major impact on public health (much greater than incidence rates would suggest) because of associated high morbidity and mortality rates.[1] Drs. Berlin and Rothenberg have written a comprehensive synopsis of the state of conventional cytotoxic chemotherapy and radiation therapy for surgically resected and advanced panc...
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