Adult Wistar rats were treated with unilateral intrastriatal injection of quinolinic acid (QA) in one single dose of 150 nM/L. The other two group of animals were pretreated with nerve growth factor (NGF) and fibroblast growth factor (FGF), respectively. Control group was treated with 0.154 mmol/L saline solution likewise. Activity of cytochrome c oxidase (COX) was decreased in the basal forebr...

The quantitative comparison of two-dimensional dose distributions (e.g., calculated versus measured) has become a key issue in intensity-modulated radiotherapy (IMRT) QA. We proposed a new evaluation method referred to as modified dose difference (MDdiff) evaluation. Hereinafter, features and effectiveness of the MDdiff evaluation method will be described. In this work, the formalism of MDdiff ...

Mouse strain background can influence vulnerability to excitotoxic neuronal cell death and potentially modulate phenotypes in transgenic mouse models of human disease. Evidence supports a contribution of excitotoxicity to the selective death of medium spiny neurons in Huntington's disease (HD). Here, we assess whether strain differences in excitotoxic vulnerability influence striatal cell death...

This paper discusses some main difficulties of restricted-domain question-answering systems, in particular the problem of precision performance. We propose methods for improving the precision, which can be classified into two main approaches: improving the Information Retrieval module, and improving its results. We present the application of these methods in a real QA system for a large company...

Theories based upon strong real space (r-space) electron-electron interactions have long predicted that unidirectional charge density modulations (CDMs) with four-unit-cell (4a0) periodicity should occur in the hole-doped cuprate Mott insulator (MI). Experimentally, however, increasing the hole density p is reported to cause the conventionally defined wavevector QA of the CDM to evolve continuo...

Cyanobacterial NDH-1 interacts with photosystem I (PSI) to form an NDH-1-PSI supercomplex. Here, we observed that absence of NDH-1 had little, if any, effect on the functional fractions of PSI under growth conditions, but significantly reduced the functional fractions of PSI when cells of Synechocystis sp. strain PCC 6803 were moved to conditions of multiple stresses. The significant reduction ...