G-quadruplex (G4)-interactive small molecules have a wide range of potential applications, not only as drugs, but also sensors quadruplex structures. The purpose this work is the synthesis analogues bis-methylquinolinium-pyridine-2,6-dicarboxamide G4 ligand 360A, to identify relevant structure–activity relationships apply design other G4-interactive bearing bis-quinoline or bis-isoquinoline moi...

eggshell was found to be a versatile heterogeneous catalyst for the synthesis of pyrano[3,2-c]quinoline derivatives in good yields. this protocol has the advantages of environmental friendliness, short reaction time, low cost and convenient operation.

In the title compound, C(27)H(26)N(2)O, the mean planes through the carbazole and quinoline ring systems form a dihedral angle of 67.23 (5)°. Mol-ecules are linked into cyclic centrosymmetric dimers by O-H⋯N hydrogen bonds, and C-H⋯π inter-actions with the pyridine ring of the quinoline ring system as an acceptor. The dimers are linked through C-H⋯O hydrogen bonds.

In the title compound, C(20)H(20)N(2)O, the dihedral angle between the quinoline ring system and the phenyl ring is 49.40 (5)°. In the crystal structure, zigzag layers of mol-ecules, in which the quinoline units are parallel to the (10) plane, are arranged perpendicular to the b axis. Inter-molecular N-H⋯O hydrogen bonds connect the mol-ecules into chains along [010], reinforcing the cohesion b...

In the title compound, C(26)H(20)ClNO(2), the quinoline ring system and the methoxy-phenyl ring form dihedral angles of 69.97 (6) and 22.10 (10)°, respectively, with the propenone linkage. The 4-phenyl ring substituent on the quinoline ring system is oriented at a dihedral angle of 66.47 (3)°. In the crystal, mol-ecules exist as C-H⋯O hydrogen-bonded dimers. The structure is further stabilized ...

The title salt, C(10)H(7)N(2) (+)·HSO(4) (-), is formed by the transfer of a proton from H(2)SO(4) to the N atom of 2-cyano-quinoline during crystallization. The quinoline ring system is approximately planar with a maximum deviation of 0.013 (3) Å. In the crystal, the cations are linked to the anions via inter-molecular N-H⋯O, O-H⋯O and C-H⋯O hydrogen bonds, forming a layered network.