نتایج جستجو برای: quiescent zone
تعداد نتایج: 122019 فیلتر نتایج به سال:
In newly hatched Drosophila larvae, quiescent cells reenter the cell cycle in response to dietary amino acids. To understand this process, we varied larval nutrition and monitored effects on cell cycle initiation and maintenance in the mitotic neuroblasts and imaginal disc cells, as well as the endoreplicating cells in other larval tissues. After cell cycle activation, mitotic and endoreplicati...
Purpose:Because chemoradiotherapy selectively targets proliferating cancer cells, quiescent cancer stem– like cells are resistant. Mobilization of the cell cycle in quiescent leukemia stem cells sensitizes them to cell death signals. However, it is unclear that mobilization of the cell cycle can eliminate quiescent cancer stem– like cells in solid cancers. Thus, we explored the use of a genetic...
Next Generation Air Traac Management will allow for the possibility of free ight, in which each aircraft chooses its own optimal route, altitude and speed. In a free ight environment, the trajectories of several aircraft may be connicting, in which case aircraft may or may not cooperate in resolving the connict. This paper presents a method for noncooperative connict resolution in which each ai...
Antineoplastic intercalating agents such as 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) stabilize a cleavable complex between topoisomerase II and DNA. The production of protein-associated DNA cleavage in whole cells exposed to m-AMSA is thought to represent the cellular correlate of this topoisomerase II-mediated reaction. Protein-associated DNA cleavage can be quantified in mammal...
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