The phytochemical investigation on the chloroform and ethyl acetate soluble fractions of Colebrookia oppositifolia Smith. led to the isolation of four new-source compounds namely 1pentacosanol (1), stigmast-7-ene-3β-ol (2), p-hydroxybenzoic acid (3), ursolic acid (4) and seven known compounds namely triacontane (5), triacontanol (6), betulonic acid (7), negletein (8), 5,2′,6′-trihydroxy-7-metho...

Four major compounds were separated and identified from the methanol extracts of Nerium indicum flowers (Arali) using HPLC and mass spectral data. Through mass data, the chemical structures were elucidated as: trans5-O-caffeoylquinic acid (1), quercetin-3-O- rutinoside (2), luteolin-5-O-rutinoside (3) and luteolin-7-O-rutinoside (4). In addition, the cis isomers of 5-O-caffeoylquinic acid in Ne...

Article history: Received on: 05/07/2017 Accepted on: 17/08/2017 Available online: 30/09/2017 The application of different chromatographic and spectroscopic techniques to the aqueous alcoholic leaves extract of Dichrostachys cinerea (L.) Wight et Arn. (Mimosaceae) led to the isolation and identification of ten phenolic compounds. Among them, apigenin-7-O-apiosyl (1→2) glucoside, chrysoeriol-7-O...

Beaumontia grandiflora Wall. (Apocynaceae) is an ornamental plant cultivated in Egypt. Investigation of the chemical constituents of the aerial parts of B. grandiflora Wall. in pet. ether extract led to isolation and identification of twelve fatty acids in which linoleic acid (29.60%) and Palmitic acid (19.12%) are the main acids. The unsaponifiable fraction was found to contain a series 14 27 ...

In addition to lotaustralin and linamarin, a novel cyanogenic glycoside, 2-((6-O-(beta-D-apiofuranosyl)-beta-D-glucopyranosyl)oxy)-2-met hylbutanenitrile , two novel non-cyanogenic glycosides, (2S)-((6-O-(beta-D-apiofuranosyl)-beta-D- glucopyranosyl)oxy)butane and 2-((6-O-(beta-D-apiofuranosyl)-beta-D-glucopyranosyl)oxy)propane, and a simple non-cyanogenic glycoside, ethyl beta-D-glucopyranosid...

Liquid chromatography, with diode array detection and electrospray ionization mass spectrometry (LC-DAD-ESI/MS), was used to identify and quantify flavonoids in cashew apple. One anthocyanin and thirteen glycosylated flavonols were detected in a methanol-water extract. Among them, the 3-O-galactoside, 3-O-glucoside, 3-O-rhamnoside, 3-O-xylopyranoside, 3-O-arabinopyranoside and 3-O-arabinofurano...

Two new flavonol glycosides, myricetin 4'-O-alpha-L-rhamnopyranoside (1) and quercetin 3'-O-alpha-L-rhamnopyranoside (2), together with a novel biflavonol compound, speciin (3), as well as eleven phenolic metabolites, namely myricitrin (4), europetin 3-O-alpha-L-(1)C(4)-rhamnopyranoside (5), quercitrin (6), hyperin (7), rhamnetin 3-O-beta-galacto-pyranoside (8), caffeic acid (9), caffeic acid m...

Quercetin, a ubiquitous flavonol, represents a promising leading drug for development of new chemotherapeutic agents. However, its limited cytotoxicity to cancer cells hampers its clinical use. In order to obtain novel quercetin derivatives with superior cytotoxicity, seven alkylated quercetin derivatives were synthesized. Solubility of these derivatives was determined by turbidimetry. Cytotoxi...

The dietary flavonoid quercetin reduces blood pressure and improves endothelial function in several rat models of hypertension. We analyzed the effects of quercetin and its methylated metabolite isorhamnetin on the aortic endothelial dysfunction induced by incubation with angiotensin II (AngII) in vitro for 6 h. AngII diminished the relaxant responses to acetylcholine in phenylephrine-contracte...