We put forward a variational framework suitable for the study of curves whose energies depend on their bend and twist degrees freedom. By employing material curvatures to describe such elastic deformation modes, we derive equilibrium equations representing balance forces torques curve. The conservation laws force torque curve, stemming from Euclidean invariance energy, allow us obtain first int...

The target mass corrections are calculated for all structure functions of neutral and charged current deep inelastic scattering in lowest order in the coupling constant. Representations of the correction to the twist–2 and twist–3 contributions are derived both in Mellin-n and x-space. The impact of the target mass corrections on the general relations between the twist–2 and twist–3 parts of th...

Cis-regulatory modules (CRMs) function by binding sequence specific transcription factors, but the relationship between in vivo physical binding and the regulatory capacity of factor-bound DNA elements remains uncertain. We investigate this relationship for the well-studied Twist factor in Drosophila melanogaster embryos by analyzing genome-wide factor occupancy and testing the functional signi...

OBJECTIVE Left ventricular (LV) rotation and twist play an important role in LV contraction and relaxation. Left bundle branch block (LBBB) deteriorates both diastolic and systolic functions. We evaluated the LV twist in patients with LBBB and preserved ejection fraction (EF) (>50%) to determine twist as a potential marker for subtle myocardial dysfunction. METHODS This observational cross-se...

BACKGROUND miRNAs are involved in osteosarcoma (OS) chemoresistance, and TWIST reportedly enhances cisplatin-induced OS cell apoptosis by inhibiting multiple signaling pathways. In this study, we profiled miRNAs differentially expressed in chemoresistant OS, with a focus to identify miRNAs that regulate TWIST expression and OS chemoresistance. METHODS OS patients who showed <90% tumor necrosi...

We investigate the helicity dependent twist-two and twist-three generalized parton distributions in light-front Hamiltonian QCD for a massive dressed quark target. Working in the kinematical region ξ < x < 1, we obtain the splitting functions for the evolutions of twist-two quark and gluon distributions in a straightforward way. For the twist-three distribution, we find that all contributions a...

The stabilization of the metastable 180 degrees twist state in a bistable chiral splay nematic liquid crystal device is studied. The stability of the metastable 180 degrees twist state is explained using the azimuthal anchoring strength, which is a function of the twist elastic constant and the cell gap. A stable 180 degrees twist state as well as the permanent retention time can be obtained by...