The present study has been aimed at investigating various Economic Parameters of the silkworm cocoon, when fed on mulberry leaves fortified with selected trace element Zinc, vitamin, Pyridoxine and hormone, Methoprene. The experimental worms were divided in to four groups and fed with mulberry leaves soaked in the selected compounds i.e. Zinc chloride, Pyridoxine, Methoprene and with Mixed dose...

We investigated the effect of pyridoxine administration in three patients with homocystinuria due to cystathionine synthase deficiency. The drug decreased the plasma concentration and urinary excretion of methionine and homocystine and the urinary excretion of homolanthionine and the homocysteine-cysteine mixed disulfide. Urinary cystine rose somewhat. Oral methionine tolerance tests before and...

Various effects of harmidine hydrochloride, an alkaloid of Peganum harmalla, have been studied in rats treated with harmidine hydrochoride 12 mg/kg body weight alone and pretreated with pyridoxine. Harmidine produced shivering, ataxia, diarrhoea, reduction in motor activity, loss of postural reflex and hypothermia. Weight of animals, respiratory rate, heart rate, urinary output, oestrous cycle,...

Isotopic data reported by Mead, Steinberg, and Howton in 1953 (1) and by Steinberg, Slaton, Howton, and Mead in 1956 (2) firmly established the incorporation of acetate and of linoleate, respectively, into arachidonic acid in the rat. Witten and Holman in 1952 (3) had suggested that pyridoxine stimulated this conversion. They had shown that rats deficient in essential fatty acids and in pyridox...

S INCE THE FIRST report in 1956 of a patient with pyridoxine-responsive anemia, a number of other patients have been reported.”2 The red blood cells usually are hypochromic and microcytic but occasionally they may be macrocytic and accompanied by megaboblastic bone marrow maturation. It is unlikely that many of these patients have a simple dietary deficiency of pyridoxine, since barge doses of ...

A cutaneous reaction termed palmar-plantar erythrodysesthesia (PPES) or hand-foot syndrome can be dose limiting for Doxil, a doxorubicin containing pegylated (Stealth) liposome. The objective of this study was to determine the ability of concomitant pyridoxine therapy to prevent the development of PPES during Doxil therapy. Forty-one dogs with non-Hodgkin's lymphoma were randomized in a double-...

The rare inherited disorder hyperprolinaemia type II presents with fits in childhood, usually precipitated by infection. A diagnosis of hyperprolinaemia type II and vitamin B(6) deficiency was made in a well nourished child with fits. It is thought that pyridoxine deficiency was implicated in her fits and was the result of inactivation of the vitamin by the proline metabolite, pyrroline-5-carbo...

Oral glucose tolerance tests were carried out in 16 clinically normal subjects with pyridoxine deficiency (as adjusted by red cell transaminase activity and the 6h tryptophan load test), and in 16 nondeficient controls. The deficient subjects had fasting normoglycemia with hypoinsulinemia (p less than 0.01), and a normal postglucose increment in insulin, but peak blood glucose and incremental g...