The corrosion inhibition performance of 2-hydrazino-4,6-dimethoxy-1,3,5-tirazine (DMeHT), 2,4-dihydrazino-6-methoxy-1,3,5-triaizine (DHMeT), and 2,4,6-tridydrazino-1,3,5-triaizne (TH₃) on steel corrosion in acidic media was examined using electrochemical techniques. The results showed 2,4-Ddihydrazino-6-methoxy-1,3,5-triaizine (DHMeT) gave the best corrosion protection performance among the oth...

Abstract Objectives A regioselective approach has been developed for the synthesis of benzopyranophenazine derivatives using In (OTf)3 as a catalyst in one‐pot synthesis. Further, these synthesized compounds were successfully used organic corrosion inhibitors on mild steel 1M H2SO4 solution. Methods The confirmed NMR, and HRMS their regioselectivity was by DFT studies B3LYP/6‐31G (d, p) basis s...

The corrosion inhibition properties of some organic dyes, namely Sunset Yellow (SS), Amaranth (AM), Allura Red (AR), Tartrazine (TZ) and Fast Green (FG), for mild steel corrosion in 0.5 M HCl solution, were investigated using gravimetric, potentiodynamic polarization techniques and quantum chemical calculations. The results showed that the studied dyes are good corrosion inhibitors with enhance...

Evaluation of corrosion inhibitors for steel in acidic media is important for some industrial facilities as well as is very interesting from theoretical aspects. Most of the effective inhibitors are organic compounds containing nitrogen, phosphorus and sulphur in their structures [1, 2]. Heteroatoms such as nitrogen, oxygen and sulphur are capable of forming coordinate covalent bond with metal ...

Inwardly rectifying potassium channels are potassium selective ion channels. In this study, the structure of inwardrectifying K + channel was analyzed following the homology modeling utilizing the crystal structure of 1ORQ (voltage dependent K + channel protein) as template from Aeropyrum pernix through MODELLER 9v1. Refined model of protein structure was obtained after energy minimization and ...

Based on structural analysis of the human 2-oxoglutarate (2OG) dependent JMJD2 histone N(ε)-methyl lysyl demethylase family, 3-substituted pyridine 2,4-dicarboxylic acids were identified as potential inhibitors with possible selectivity over other human 2OG oxygenases. Microwave-assisted palladium-catalysed cross coupling methodology was developed to install a diverse set of substituents on the...

The melting curves of fatty acid amide hydrolase (FAAH) in the presence of 29 reversible inhibitors were measured using a thiol-reactive fluorophore. The thermal stability (T(m)) of the FAAH/inhibitor complex varied significantly depending on the chemical characteristics of the inhibitors, notably variations in the head group. Two separate distributions were observed when T(m) was plotted again...

Fluorination is a well-known strategy for improving the bioavailability of drug molecules. However, its impact on efficacy is not easily predicted. On the basis of inhibitor-bound protein crystal structures, we found a beneficial fluorination spot for inhibitors targeting methionyl-tRNA synthetase of Trypanosoma brucei. In particular, incorporating 5-fluoroimidazo[4,5-b]pyridine into inhibitors...