BACKGROUND Transseptal (TS) catheterization is needed to access the left heart during pulmonary vein isolation (PVI) procedures. In the radiofrequency (RF) ablation procedure, left atrial access is commonly achieved with a double TS puncture; cryoballoon (CB) ablation usually requires only a single TS puncture. Our aim was to compare the incidence of iatrogenic septal defect (IASD) between doub...

The sixth Painlevé equation arises from a Drinfeld-Sokolov hierarchy of type D (1) 4 by similarity reduction. 2000 Mathematics Subject Classification: 34M55, 17B80, 37K10. Introduction The Drinfeld-Sokolov hierarchies are extensions of the KdV (or mKdV) hierarchy [DS]. It is known that their similarity reductions imply several Painlevé equations [AS, KK1, NY1]. For the sixth Painlevé equation (...

Pulmonary vein isolation (PVI) with radio-frequency catheter ablation (RFCA) is effective therapy for the patients with paroxysmal atrial fibrillation (pAF). However, it is not easy to predict relapse of pAF. Approximately 70% pAF patients were maintained sinus rhythm for 1 year after PVI in Japan. In this study, all of the cases were underwent chest computed tomography (CT) to check for the mo...

Atrial fibrillation affects an estimated 2.7–6.1 million people in the United States and accounts for more than 750,000 hospitalizations per year. Pulmonary vein isolation (PVI) has been well established as the most effective ablation treatment available for patients with symptomatic and medication-refractory atrial fibrillation. Previously, radiofrequency (RF) ablation was the mainstay for PVI...

Abstract. This paper provides convergence analysis of regularized time-stepping methods for the differential variational inequality (DVI), which consists of a system of ordinary differential equations and a parametric variational inequality (PVI) as the constraint. The PVI often has multiple solutions at each step of a time-stepping method and it is hard to choose an appropriate solution for gu...

A sensitive d-amino acid oxidase (DAAO)/peroxidase (POD) bienzyme biosensor is constructed, in which pentacyanoferrate-bound poly(1-vinylimidazole) polymer (PVI[Fe(CN)5]) is selected as a mediator. Reductive current of PVI[Fe(CN)5] related to the H2O2 concentration generated in the DAAO reaction was measured at -0.1V vs. Ag|AgCl with DAAO/POD/PVI[Fe(CN)5]-modified electrode. The result revealed...

BACKGROUND The limited efficacy and complications of segmental ostial pulmonary vein isolation (PVI) for treating atrial fibrillation (AF) have been discussed so, in the present study the feasibility and efficiency of performing segmental pulmonary vein (PV) antrum isolation to treat AF were assessed. METHODS AND RESULTS A total of 187 patients with drug-refractory AF (paroxysmal 120, persist...

INTRODUCTION Recurrent atrial fibrillation (AF) after ablation is associated with reconnection of initially isolated pulmonary vein (PV) trigger sites. Substrates are often targeted in addition to PVI, but it is unclear how substrates progress over time. We studied if substrates in recurrent AF are conserved or have developed de novo from pre-ablation AF. METHODS AND RESULTS Of 137 patients u...

Abstract Funding Acknowledgements Type of funding sources: None. Introduction The CLOSE protocol was developed as a radiofrequency ablation strategy that would result in the safe creation durable pulmonary vein isolation (PVI) leading to improved outcomes. aim is enclose PVs with stable, contiguous and index (AI) guided lesions. Purpose We analyze arrhythmic substrate found patients undergoing ...

Pulmonary vein isolation (PVI) is the cornerstone interventional treatment for AF but success of this approach more limited in persistent (PsAF). In these pts, main challenge to discriminate those who will respond PVI only, from may require an extended ablation strategy. We sought characterize patterns electrical activity recorded within PVs based on their postulated contribution mechanism PsAF...