This paper addresses the architectural issues that arise in the design of a universally accessible wide-area network-computing system that is capable of making automatic cost/performance tradeoo decisions at run-time. The core system is designed around a three-level hierarchically distributed architecture, a choice driven by the dynamic, incremental, and distributed nature of the information as...

OBJECTIVE To determine if healing of punch biopsy wounds by second intention is equivalent to healing with primary closure. DESIGN Prospective, randomized, method comparison equivalence study. SETTING Tertiary academic medical center. PARTICIPANTS Study volunteers were recruited from the general population and enrolled between January 7, 2002, and August 20, 2002. Patients with immunodefi...

Plastic heterogeneity in indentation is fundamental for understanding mechanics of hardness testing and impression-based deformation processing methods. The heterogeneous deformation underlying plane-strain indentation was investigated in plastic loading of copper by a flat punch. Deformation parameters were measured, in situ, by tracking the motion of asperities in high-speed optical imaging. ...

Thick smoke routinely cloaks Southern California hills, highways, and neighborhoods during this region’s autumn wildfire season, with drought contributing to worse fires than usual in the past two years. Wildfire emissions generate larger aerosols than those produced by vehicles—up to 0.4 micrometers (μm) in diameter compared with less than 0.15 μm—according to a new study led by Constantinos S...

Computer architecture educators and researchers increasingly depend on the use of sophisticated software tools to investigate and evaluate designs of computer systems and their components. Currently, computer architecture CAD (computer-aided design) in universities relies on locally built tools or on public-domain software developed by small research groups. Such groups have limited resources a...

INTRODUCTION Gingiva is a common site for reactive, non-neoplastic, and neoplastic lesions with unspecific clinical features (Fig. 1): desquamative gingivitis as expression of mucocutaneous diseases (lichen planus, pemphigus, pemphigoid, plasma-cell gingivitis, lupus erythematosus), preneoplastic lesions (gingival verrucous proliferative leukoplakia), and gingival enlargements (gingival fibroma...

Certain problems in which a cooled rigid punch indents an elastic half-space have no steady state solution. A simple model is described in which it is shown that this paradox is avoided by the assumption of a thermal resistance varying inversely with contact pressure. A limiting case of this system retains linearity and introduces a state of "imperfect" contact in which contact pressure is negl...