Vital Pulp Protection and Therapy (VPPT) is the treatment that maintains pulp tissue in a healthy and functional state, whenever the dentin-pulp complex has been compromised by caries, trauma or restorative procedures. Pulp vitality and function is not essential for mature tooth survival. Mature permanent teeth without a vital pulp can survive for a long time after a successful endodontic treat...

INTRODUCTION Direct pulp capping procedure is a therapeutic application of a drug on exposed tooth pulp in order to ensure the closure of the pulp chamber and to allow the healing process to take place. OBJECTIVE The aim of this study was to examine the histological effects of Emdogain® on exposed tooth pulp of a Vietnamese pig (Sus scrofa verus). METHODS The study comprised 20 teeth of a V...

Endodontic regeneration shows promise in treating dental pulp diseases; however, no suitable scaffolds exist for pulp regeneration. Acellular natural extracellular matrix (ECM) is a favorable scaffold for tissue regeneration since the anatomical structure and ECM of the natural tissues or organs are well-preserved. Xenogeneic ECM is superior to autologous or allogeneic ECM in tissue engineering...

We have isolated dental pulp cells (DPCs) from three healthy (hDPCs) and three carious (cDPCs) donors and shown that compared to hDPCs cells isolated from superficial carious lesions show higher clonogenic potential; show an equivalent proportion of cells with putative stem cell surface markers; show enhanced matrix mineralization capability; have enhanced angiogenic marker expression and retai...

The purpose of this study was to assess the histological appearance of the pulp of human primary incisors extracted because of deep, unrestorable caries, and to determine how clinical pulp exposures affected the histological status of the pulp compared to nonexposures. Caries was removed carefully from all teeth after fixation; 24 incisors had pulp exposures, and 29 teeth had no pulp exposures....

Regenerative endodontics aims to replace inflamed/necrotic pulp tissues with regenerated pulp-like tissues to revitalize teeth and improve life quality. Pulp revascularization case reports, which showed successful clinical and radiographic outcomes, indicated the possible clinical application of pulp regeneration via cell homing strategy. From a clinical point of view, functional pulp-like tiss...

introduction: the aim of this study was to determine the histologic effect of low level laser therapy (lllt) with or without the use of mineral trioxide aggregate (mta) on exposed pulp tissues of dogs. methods: twenty-five premolar teeth in three healthy mature dogs were randomly divided into five groups. in group 1, the pulp tissue was capped with mta. in groups 2 and 3, before capping with mt...

i ntroduction: the aim of this study was to evaluate the clinical and histological status of the pulp in sound human premolars after direct pulp capping (dpc) with four different dpc methods/materials. methods and materials: this study was conducted on eight volunteers who had to extract four first premolars due to orthodontic treatment. subsequent to tooth isolation, standardized class i occlu...