Various forms of psychotic disorders, including schizophrenia, can influence how we speak. Therefore, clinicians assess speech and language behaviors of their patients. While it is difficult for humans to quantify speech behaviors precisely, acoustic descriptors, such as tenseness of voice and speech rate, can be quantified automatically. In this work, we identify previously unstudied acoustic ...

Considerable data support the phenomenological and temporal continuity between subclinical psychosis and psychotic disorders. In recent years, neurocognitive deficits have increasingly been recognized as a core feature of psychotic illness but there are few data seeking to elucidate the relationship between subclinical psychosis and neurocogntive deficits in non-clinical samples. The goal of th...

AIM To examine possible causal linkages between cannabis use and psychosis using data gathered over the course of a 25-year longitudinal study. DESIGN A 25-year longitudinal study of the health, development and adjustment of a birth cohort of 1265 New Zealand children (635 males, 630 females). SETTING The Christchurch Health and Development Study, a general community sample. PARTICIPANTS ...

BACKGROUND There is increased risk of developing psychosis in 22q11.2 deletion syndrome (22q11DS). Although this condition is associated with morphologic brain abnormalities, simultaneous examination of multiple high-resolution measures of cortical structure has not been performed. METHODS Fifty-three patients with 22q11DS, 30 with psychotic symptoms, were compared with demographically matche...

BACKGROUND Schizotypy is a range of perceptual experiences and personality features related to risk and familial predisposition to psychosis. Despite evidence that schizotypy is related to psychosis vulnerability, very little is known about the expression of schizotypal traits in individuals with a psychotic disorder, and their relationship to clinical symptoms, cognition, and psychosocial func...

OBJECTIVE Neurodevelopmental theories of psychosis highlight the potential benefits of early intervention, prevention, and/or preemption. How early intervention should take place has not been established, nor whether interventions based on social learning principles can have preemptive effects. The objective was to test whether a comprehensive psychosocial intervention can significantly alter p...

OBJECTIVE Poor premorbid adjustment has been reported to be a predictor of more severe psychotic symptoms and poor quality of life in such psychotic disorders as schizophrenia. However, most studies were performed on chronic schizophrenic patients, and proposed the likelihood of recall biases and the effect of chronicity. The aim of this study was to investigate these factors in a sample of fir...

Individuals with psychosis have an increased risk of committing acts violence. Providing neurobiological evidence for the extent to which violence in is driven by psychotic symptoms and/or antisocial traits could important clinical and legal implications. White matter (WM) abnormalities been reported individuals those traits. However, it not clear if WM violent (violent PSY) resemble previously...

The main subject of criminal proceedings is that of criminal responsibility, from this point of view bipolar disorders sometimes seem to be a neglected subject in legal scholarship. Yet they may affect decision-making across the spectrum of the law, especially when manic and psychotic symptoms are implicated. This case studies a 37-year-old woman, diagnosed with bipolar affective in disorder, w...