Progressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by extensive neurofibrillary tangle (NFT) formation and neuronal loss in selective neuronal populations. Currently, no clues to the biological events underlying the pathological process have emerged. In Alzheimer disease (AD), which shares with PSP the occurrence of NFTs, advanced glycation end products (AGEs) as...

Periplocoside P (PSP) isolated from the root bark of Periploca sepium contains a pregnane glycoside skeleton and possesses high insecticidal properties. Preliminary studies indicated that PSP disrupts epithelial functions in the midgut of lepidopteran larvae. In the present study, we examined the effects of PSP on the apical and basolateral membrane voltages, Va and Vbl, respectively, of cells ...

Primary spontaneous pneumothorax (PSP) affects young healthy people with a significant recurrence rate. Recent advances in treatment have been variably implemented in clinical practice. This statement reviews the latest developments and concepts to improve clinical management and stimulate further research.The European Respiratory Society's Scientific Committee established a multidisciplinary t...

It is not known whether the integration of photo-stimulable phosphor (PSP) plates into dental and dental hygiene curricula creates unique learning challenges for students. The purpose of this two-year study was to determine if dental hygiene students had more and/or different types of errors when using PSP plates compared to film and whether the PSP imaging plates had any particular characteris...

High-density lipoprotein (HDL) is part of innate immunity, protecting against infection and inflammation. Using a proteomic approach, we identified an amino acid sequence in a hamster HDL protein that showed homology to rat and mouse parotid secretory protein (PSP), a salivary protein secreted from the parotid glands. We cloned the cDNA encoding a putative hamster homolog of rat and mouse PSP. ...

BACKGROUND AND PURPOSE Quantitative evaluation of midbrain atrophy may be useful in differentiating progressive supranulear palsy (PSP) from Parkinson disease (PD); however, this finding is not specific of PSP, and quantitative measurements are not always practical. We determined whether an abnormal superior midbrain profile (flat or concave aspect) is a more practical diagnostic parameter for ...

Lp16-PSP (Latcripin 16-Perchloric acid Soluble Protein) from Lentinula edodes strain C91-3 has been reported previously in our laboratory to have selective cytotoxic activity against a panel of human cell lines. Herein, we have used several parameters in order to characterize the Lp16-PSP-induced cell death using human acute promyeloid leukemia (HL-60) as a model cancer. The results of phase co...

This work introduces the use of GradedChannel SOI MOSFETs to make analog current mirrors and compare their performance with those made with conventional fully depleted SOI transistors. It is demonstrated that Graded-Channel MOSFETs can provide higher precision current mirror with enhanced output swing. Also lesser modifications of the output characteristics due to the self-heating effect than i...

A current-mode output driver that supports SERDES applications is implemented using 0.13 μm Bulk and PD SOI CMOS technologies. Schematic simulation results confirm the enhanced performance of PD SOI for very high-speed interfaces. The PD SOI current-mode driver shows a 3 times lower data dependent jitter than the Bulk current-mode driver at the same 3.125 Gbps data rate of XAUI standard.

Can private sector participation (PSP) in the piped water sector improve child health? I use child-level data from 39 African countries during 1986-2010 to show that PSP decreases diarrhea among urban-dwelling, under-five children by 2.6 percentage points, or 16% of its mean prevalence. Children from the poorest households benefit most. PSP is also associated with a 7.8 percentage point increas...