نتایج جستجو برای: psoralea drupacea

تعداد نتایج: 258  

2014
Wenhui Hao Xuenong Zhang Wenwen Zhao Xiuping Chen Joao Rocha

Psoralidin (PSO), a natural furanocoumarin, is isolated from Psoralea corylifolia L. possessing anti-cancer properties. However, the mechanisms of its effects remain unclear. Herein, we investigated its anti-proliferative effect and potential approaches of action on human lung cancer A549 cells. Cell proliferation and death were measured by MTT and LDH assay respectively. Apoptosis was detected...

2018
Chi-Yuan Chen Chin-Chuan Chen Tzong-Ming Shieh Chuen Hsueh Shu-Huei Wang Yann-Lii Leu Jang-Hau Lian Tong-Hong Wang

Corylin is a flavonoid extracted from the nuts of Psoralea corylifolia L. (Fabaceae), which is a widely used anti-inflammatory and anticancer herb in China. Recent studies revealed antioxidant, anti-inflammatory, and bone differentiation-promoting effects of corylin. However, there are no studies examining the anticancer activity of corylin. In this study, we used cells and animal models to exa...

Journal: :Molecules 2012
Joanna Bronikowska Ewelina Szliszka Dagmara Jaworska Zenon P Czuba Wojciech Krol

Coumarins are a very common type of secondary plant metabolites with a broad spectrum of biological activities. Psoralidin is a naturally occurring furanocoumarin isolated from Psoralea corylifolia possessing anticancer and chemopreventive properties. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) triggers apoptosis in cancer cells with no toxicity toward normal tissues. Endoge...

2017
Yung-Li Hung Shih-Hua Fang Shu-Chi Wang Wei-Chung Cheng Po-Len Liu Chia-Cheng Su Chi-Shuo Chen Ming-Yii Huang Kuo-Feng Hua Kun-Hung Shen Yu-Ting Wang Katsuhiko Suzuki Chia-Yang Li

Corylin is a main compound isolated from Psoralea corylifolia L. (Fabaceae). A variety of pharmacological effects such as antioxidant, anti-proliferation, and anti-inflammatory properties of corylin have been reported. Nevertheless, the effect of corylin in microbial infection and sepsis remains unclear. In the present study, we investigated the anti-inflammatory effects of corylin. Our experim...

2014
Lina Shan Shuman Yang Gang Zhang Dun Zhou Zhenyu Qiu Lei Tian Hongxia Yuan Yujun Feng Xianbao Shi

Bavachalcone and corylin are two major bioactive compounds isolated from Psoralea corylifolia L., which has been widely used as traditional Chinese medicine for many years. As two antibiotic or anticancer drugs, bavachalcone and corylin are used in combination with other drugs; thus it is necessary to evaluate potential pharmacokinetic herb-drug interactions (HDI) of the two bioactive compounds...

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