Early and late puberty pose a risk for many problems later in life. Various theories suggest that child sexual abuse victimization may either accelerate or delay the onset of puberty. This systematic literature review examines relationship between age girls. Fourteen scientific studies were included analyzed. There is an association early at menarche girls, but there insufficient evidence with ...

Puberty is a key developmental event whose primary regulatory mechanisms remain poorly understood. Precise dating of puberty is crucial for experimental (preclinical) studies on its complex neuroendocrine controlling networks. In female laboratory rodents, external signs of puberty, such as vaginal opening (VO) and epithelial cell cornification (i.e., first vaginal estrus, FE), are indirectly r...

There are still no highly sensitive and unique biomarkers for measurement of puberty onset. Circulating miRNAs have been shown to be promising biomarkers for diagnosis of various diseases. To identify circulating miRNAs that could be served as biomarkers for measuring chicken (Gallus gallus) puberty onset, the Solexa deep sequencing was performed to analyze the miRNA expression profiles in seru...

CONTEXT Initiation and progression of puberty requires concerted action of hypothalamic activating and inhibiting factors. Recently, cases of familial central precocious puberty have been linked to loss-of-function mutations of makorin RING-finger protein 3 (MKRN3) indicating a pivotal inhibitory role of the protein on GnRH secretion. OBJECTIVE To investigate peripubertal circulating MKRN3 le...

During development, an increase in gonadotropin-releasing hormone (GnRH) release occurs that is critical for the initiation of puberty. This increase is attributable, at least in part, to activation of the GnRH neurosecretory system by inputs from neurotransmitters, such as glutamate, acting via NMDA receptors. We examined changes in GnRH and NMDA-R1 gene expression by RNase protection assay of...

BACKGROUND AND OBJECTIVE Studies of the relationship of weight status with timing of puberty in boys have been mixed. This study examined whether overweight and obesity are associated with differences in the timing of puberty in US boys. METHODS We reanalyzed recent community-based pubertal data from the American Academy of Pediatrics' Pediatric Research in Office Settings study in which trai...

INTRODUCTION Delayed pubertal maturation has been reported in girls with type 1 diabetes. OBJECTIVES To report the age of onset of puberty and menarche in girls with type 1 diabetes diagnosed before puberty. To investigate clinical factors affecting the occurrence of puberty and menarche in this population. PATIENTS AND METHODS A retrospective study of 38 girls with type 1 diabetes, all of ...

Abstract: Puberty is an important stage of human life. Several physiological alterations accompanying the teenage years manifest themselves in often complex and curious means to which females show different reactions. Even though this a female's life normal, it associated with some degree suffering embarrassment, mainly due sense hesitation. The main event puberty onset menstrual cycle; menstru...

OBJECTIVE To verify if the frequency of spontaneous pubertal development among girls with Turner syndrome (TS) diagnosed in infancy and childhood is greater than that of patients diagnosed later. SUBJECTS AND METHODS Thirty three girls aged < 10 years at the time of diagnosis were evaluated regarding pubertal development. The frequency of spontaneous puberty was compared with that of girls ag...

Puberty prepares mammals to sexually reproduce during adolescence. It is also hypothesized to invoke a social metamorphosis that prepares adolescents to take on adult social roles. We provide the first evidence to support this hypothesis in humans and show that pubertal development retunes the face-processing system from a caregiver bias to a peer bias. Prior to puberty, children exhibit enhanc...