نتایج جستجو برای: pseudoplastic

تعداد نتایج: 317  

Journal: :Drug delivery 2006
Amal El-Kamel Heba Al-Dosari Fahad Al-Jenoobi

Environmentally responsive gel formulation for ocular controlled delivery of carteolol hydrochloride (HCl) was developed in an attempt to improve ocular bioavailability and hence decrease its systemic absorption and side effects. The viscosity and the ability of the prepared formulations to deliver carteolol HCl in vitro and in vivo were monitored and compared with an aqueous commercial solutio...

2010
A. I. Hussain

Series of emulsion lattices having different composition ratios of styrene/butyl acrylate (St/BuA) as base monomers in conjunction with acrylic acid (AA) and/or methacrylic (MAA) were prepared and characterized. The preparation was carried out in industrial scale in semi batch reactor at pH range of 3-5 using potassium persulphate (KPS) as an initiator, sodium luaryl sulphate (SLS) as an emulsi...

2014
A. O. Dileep

23 The rheological and functional properties of gelatin from the skin of bigeye 24 snapper (Priacanthus hamrur) fish were assessed. The protein content of dried gelatin 25 was 94.6% and moisture content was 4.2 %. The amino acid profile of gelatin revealed 26 high proportion of glycine and imino acids. The bloom strength of solidified gelatin was 27 108 g. The average molecular weight of fish s...

2015
Emilia Szymańska Katarzyna Sosnowska Wojciech Miltyk Małgorzata Rusak Anna Basa Katarzyna Winnicka Jianxun Ding

Mucoadhesive gelling systems based on chitosan and chitosan/β-glycerophosphate (β-GP) were developed in order to increase clotrimazole residence time in the vaginal cavity. Ex vivo mucoadhesiveness using porcine vaginal mucosa followed with mechanical, viscoelastic, and swelling properties of prepared hydrogels were evaluated. Drug-free, sterile, unmodified, and β-GP crosslinked chitosan were i...

2013
Sinem Yaprak Karavana Seda Rençber Zeynep Ay Şenyiğit Esra Baloğlu

In this paper, mucoadhesive in-situ gel with poloxamer and hydroxypropylmethylcellulose formulations of itraconazole were prepared for vaginal application. In addition, rheological, mechanical and mucoadhesive properties and syringeability of the formulations were characterized. The mixtures of Poloxamer 407 and 188 with two different types of hydroxypropylmethylcellulose were used as polymers ...

2014
Armin Mooranian Rebecca Negrulj Nigel Chen-Tan Hesham S Al-Sallami Zhongxiang Fang TK Mukkur Momir Mikov Svetlana Golocorbin-Kon Marc Fakhoury Gerald F Watts Vance Matthews Frank Arfuso Hani Al-Salami

INTRODUCTION In previous studies, we successfully designed complex multicompartmental microcapsules as a platform for the oral targeted delivery of lipophilic drugs in type 2 diabetes (T2D). Probucol (PB) is an antihyperlipidemic and antioxidant drug with the potential to show benefits in T2D. We aimed to create a novel microencapsulated formulation of PB and to examine the shape, size, and che...

2014
Maira Rubi Segura-Campos Norma Ciau-Solís Gabriel Rosado-Rubio Luis Chel-Guerrero David Betancur-Ancona

Chia (Salvia hispanica L.) constitutes a potential alternative raw material and ingredient in food industry applications due to its dietary fiber content. Gum can be extracted from its dietary fiber fractions for use as an additive to control viscosity, stability, texture, and consistency in food systems. The gum extracted from chia seeds was characterized to determine their quality and potenti...

Journal: :Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2009
R Charyulu Narayana N M Harish Mohammed Gulzar A Prabhu Prabhakara Amit Kumar Singh E V S Subrahmanyam

Gel dosage forms are successfully used as drug delivery systems considering their ability to prolong the drug release. The main objective is to formulate and evaluate in situ vaginal gels of secnidazole, based on ion activated systems. The system utilizes polymers that exhibit sol-to-gel phase transition due to change in specific physico chemical parameters. Ion triggered system using gellan gu...

2014
Gisela Bevilacqua Rolfsen Ferreira da Silva Maria Virginia Scarpa Gustavo Rossanezi Eryvaldo Socrates Tabosa do Egito Anselmo Gomes de Oliveira

Microemulsions (MEs) are colloidal systems that can be used for drug-delivery and drug-targeting purposes. These systems are able to incorporate drugs modifying bioavailability and stability and reducing toxic effects. The jasmonate compounds belong to a group of plant stress hormones, and the jasmonic acid and its methyl ester derivative have been described as having anticancer activity. Howev...

2014
Maria Papagianni

The use of filamentous fungi for the production of commercially important products is old but keeps increasing during the last decades. New classes of compounds are being added in the list of products of fungal fermentations as a result of progress in methodologies and applications of biotechnology. Fungi are morphologically complex organisms that differ in structure throughout their life cycle...

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