نتایج جستجو برای: protected α

تعداد نتایج: 218898  

Journal: :European journal of immunology 2012
Henry J McSorley Mary T O'Gorman Natalie Blair Tara E Sutherland Kara J Filbey Rick M Maizels

Allergic asthma is less prevalent in countries with parasitic helminth infections, and mice infected with parasites such as Heligmosomoides polygyrus are protected from allergic airway inflammation. To establish whether suppression of allergy could be mediated by soluble products of this helminth, we tested H. polygyrus excretory-secretory (HES) material for its ability to impair allergic infla...

2012
Markus Blaukopf Bernhard Müller Andreas Hofinger Paul Kosma

Disaccharides that contain 3-deoxy-d-manno-oct-2-ulosonic acid (Kdo) and d-glycero-d-talo-oct-2-ulosonic acid (Ko) substituted at the 8-position by 4-amino-4-deoxy-β-l-arabinopyranosyl (Ara4N) residues have been prepared. Coupling an N-phenyltrifluoroacetimidate-4-azido-4-deoxy-l-arabinosylglycosyl donor to acetyl-protected allyl glycosides of Kdo and Ko afforded anomeric mixtures of disacchari...

Objective(s): The objective of this study was to investigate the hepatoprotective effect of licochalcone B (LCB) in a mice model of carbon tetrachloride (CCl4)-induced liver toxicity. Materials and Methods: Hepatotoxicity was induced in mice by a single subcutaneous injection (SC) of CCl4. The LCB was administered orally once a day for seven days (PO) as pretreatment at three doses of 1, 5, and...

2018
Sudeep Chenna Narendra Jaya Prakash Chalise Sophie Biggs Ulrich Kalinke Mattias Magnusson

Objective CD4+FoxP3+CD25+ regulatory T-cells (Tregs) are important for preventing tissue destruction. Here, we investigate the role of Tregs for protection against experimental arthritis by IFN-α. Methods Arthritis was triggered by intra-articular injection of methylated bovine serum albumin (mBSA) in wild-type mice, Foxp3DTReGFP+/- mice [allowing selective depletion of Tregs by diphtheria to...

1996
Li Rufeng

The non-adiabatic frequencies of a standard solar model are discussed in this paper. The physics describing the radiative losses is included in the non-adiabatic effects.An asymptotic approximation to the non-adiabatic non-radial p-modes of the Sun is developed. An exact solution of non-adiabatic oscillations, which results in an eigenfrequency equation with the model-dependent surface phase sh...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه زابل - دانشکده علوم 1393

سرطان بیماری، مهلکی است که بعد از بیماری های قلبی و عروقی دومین عامل مرگ و میر در جهان می باشد. سرطان پستان یکی از شایع ترین سرطان های شناخته شده و علت اصلی ناشی ازمرگ و میر سرطان در زنان می باشد. عوامل ژنتیکی و محیطی بسیاری در ابتلا به این بیماری اثر دارد. یکی از مهم ترین عوامل خطر ساز محیطی، سیگار کشیدن می باشد که نیکوتین موجود در سیگار، با اتصال به گیرنده استیل کولین نیکوتین باعث تحریک تقسیم...

Journal: :Diabetes 2017
Yuyan Xiong Gautham Yepuri Sevil Necetin Jean-Pierre Montani Xiu-Fen Ming Zhihong Yang

Aging is associated with glucose intolerance. Arginase-II (Arg-II), the type-II L-arginine-ureahydrolase, is highly expressed in pancreas. However, its role in regulation of pancreatic β-cell function is not known. Here we show that female (not male) mice deficient in Arg-II (Arg-II-/-) are protected from age-associated glucose intolerance and reveal greater glucose induced-insulin release, lar...

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