Benign Prostatic Hyperplasia and Prostate Cancer The symptoms associated with benign prostatic hyperplasia can also be caused by prostatic cancer, though they are far more likely to be due to benign overgrowth. Men with BPH do not have a higher incidence of prostate cancer (Coley 1997). The relatively high rate of prostate cancer in the general population, however, requires that an accurate dia...

OBJECTIVE To establish and verify the utility of measuring urine prostate cancer antigen 3 (PCA3) mRNA levels in the diagnosis of prostate cancer among Hong Kong Chinese patients. DESIGN Cross-sectional study. SETTING Urology Unit of a regional hospital in Hong Kong. PATIENTS This study was carried out in two parts. In the first part, 102 post-prostatic massage urine samples were collecte...

Notch signaling has been widely demonstrated to be responsible for cell fate determination during normal development and implicated in human T-cell leukemia and mouse mammary carcinomas. Here we show that Notch signaling may be involved in prostatic development and cancer cell growth. In situ hybridization and reverse transcription-PCR analyses revealed that Notch1 was expressed in prostate epi...

We have observed that the serum proteins of patients with advanced prostatic cancer rapidly return to or toward normal values following de activation of the neoplasm by anti-androgenic procedures. While there exists a variety of meth ods, more or less satifactory, for observing these changes, perhaps none is so simple or so useful as the determination of the lowest percentage of blood serum to ...

Objective: To determine the diagnostic accuracy of PSA density in Prostate Cancer, Benign Prostatic Hyperplasia (BPH) and Prostatitis, taking biopsy as gold standard.
 Study Design: Cross-sectional study.
 Place Duration Study: Chemical Pathology Endocrinology Department, Armed Forces Institute (AFIP) collaboration with Histopathology department, AFIP, Urology (AFIU) Radiology (AFIRI)...

Metastasis to the testis is rare. The site of primary tumor may be the lungs, the prostate or the large bowel. The clinical parameter is illustrated by a case history. The immunohistochemical method is taken into account. P. Lyngdorf, MD, Rørmoseparken 44, DK-3450 Allerød (Denmark) Introduction Metastasis to the testis is a rare condition [1]. Most often the site of primary tumors is in the lun...

We compared electrophoretic evaluation of acid phosphatase isoenzymes with spectrophotometric determination of prostatic acid phosphatase in terms of clinical utility. In all of 33 cases of prostatic carcinoma, an increased prostatic fraction was detected; in nine prostatectomized patients, this fraction returned to normal as measured by either technique. Abnormal spectrophotometric results wer...

Introduction: Prostate cancer is a multifaceted disease comprises distinct biological subtypes with varied spectrum of clinical, pathologic and molecular features with different prognostic and therapeutic implications. Over the last few decades there have been outstanding advances in prostate cancer management leading to earlier detection of disease. Prostatic cancer diagnosis is based on a com...

The aim of this study was to detect the differences in 90K/Mac-2BP expression in prostate cancer, benign prostatic hyperplasia and normal prostate tissues, as well as to study the significance of 90K/Mac-2BP in the early diagnosis and prognosis of prostate cancer. Comparative proteomic technologies were used in the present study. Total protein from 10 cases of prostate cancer, benign prostatic ...

Background: Autopsy study is used to disclose many hidden prostatic pathologies and their incidence. Thecurrent aims evaluate the histopathological pattern of lesions such as nodular hyperplasia ofthe prostate, precancerous lesions, latent cancer in autopsy series males over age 50 correlatethem with age.Methods: The present was a prospective carried out pathology department, afteren bloc harve...