PURPOSE The aim of this work is to evaluate results of prostate transperineal saturation biopsy as a guide for focal high-dose-rate brachytherapy in patients with prostate cancer (PCa). MATERIAL AND METHODS Template guided saturation biopsy was performed in 67 primary patients with suspicion for prostate cancer. Biopsy was performed under ultrasonography (US) control with the help of brachyth...

BACKGROUND: An accurate diagnosis is essential for the effective treatment of prostate cancer (PCa) and patients’ well-being. AIM: Thе main purpose this study was to assess utility multiparametric magnetic resonance imaging (mp-MRI) initial detection PCa among Bulgarian population men with diseases. MATERIALS AND METHODS: Fifty-three patients, aged 44 82 years, were evaluated clinically signifi...

Aim. The aim of this study is to evaluate whether leaving the biopsy needle used during prostate needle biopsy in 10% povidone-iodine (betadine) solution affects the infectious complications forming after biopsy. Material and Method. This study retrospectively evaluated the data of 176 patients with prostate biopsy performed between December 2012 and April 2014. Patients in Group 1 (n = 89) wer...

PURPOSE We developed an effective way to precisely diagnose prostate cancer using a novel prostate biopsy system that integrates pre-interventional magnetic resonance imaging with peri-interventional ultrasound for perineal navigated prostate biopsy. MATERIALS AND METHODS A total of 106 men with findings suspicious for prostate cancer (median age 66 years, prostate specific antigen 8.0 ng/ml ...

RATIONALE AND OBJECTIVES The purpose of this study was to determine the cost-effectiveness of prostate biopsy at different excess prostate-specific antigen (PSA) levels as a function of age. METHODS Medical decision analysis was performed with standard software (SMLTREE) to determine marginal effectiveness in quality adjusted life years (QALYs) and marginal cost-effectiveness in dollars per Q...

BACKGROUND There is currently no evidence in the South African (SA) literature to suggest how long patients with clinically suspected prostate cancer (an elevated prostate-specific antigen level or abnormal findings on digital rectal examination) wait to have a prostate biopsy. OBJECTIVES To improve the overall efficiency of the prostate biopsy service offered at St Aidans Regional Hospital, ...

Objectives: In this study we sought to evaluate whether elastography targeted biopsy improves the detection rate of PCa (prostate cancer) compared to systematic biopsy guided by conventional grayscale ultrasound (GSU). Materials and method: We conducted a prospective study and enrolled 240 patients on which we performed a 12 core prostate biopsy by conventional ultrasound guidence or elastograp...

BACKGROUND Chronic inflammation is hypothesized to influence prostate cancer development, although a definitive link has not been established. METHODS Prostate cancer cases (N = 191) detected on a for-cause (clinically indicated) or end-of-study (protocol directed) biopsy, and frequency-matched controls (N = 209), defined as negative for cancer on an end-of-study biopsy, were sampled from the...

PURPOSE Transrectal ultrasound (TRUS)-guided biopsy of the prostate is usually safe. However, some patients are hospitalized owing to complications from TRUS biopsy. We identified the risk factors for complications and effective preventive measures for treating complications after TRUS biopsy. MATERIALS AND METHODS Medical records and radiological images of 1,083 patients who underwent TRUS b...

PURPOSE Prostate-specific antigen (PSA) is the most important marker in the diagnosis and follow-up of patients with prostate cancer. The primary objective of this study was to evaluate the effect of various urologic procedures in prostatic area on serum free and total PSA levels. SUBJECTS AND METHODS A series of 62 patients (8 after digital rectal examination [DRE], 12 after transrectal ultr...