نتایج جستجو برای: propranolol up regulates leptin in ovariectomized rat

تعداد نتایج: 17112118  

2006

L-NAME (1 10 mM, 30 min of incubation) potentiates the tension developed (Td) in the isolated rat hemidiaphragm stimulated by direct subtetanic electrical stimulation (DSES) (F = 14 Hz). The aim of our study was to investigate the possible modulatory effect of local anaesthetic (lidocaine) and beta adrenergic blockers, propranolol and atenolol, on the L-NAMEinduced potentiation of isometric con...

Journal: :Diabetes 2003
Younes Anini Patricia L Brubaker

Glucagon-like peptide-1 (GLP-1), released from intestinal endocrine L cells, is a potent insulinotropic hormone. GLP-1 secretion is diminished in obese patients. Because obesity is linked to abnormal leptin signaling, we hypothesized that leptin may modulate GLP-1 secretion. Leptin significantly stimulated GLP-1 secretion (by up to 250% of control) from fetal rat intestinal cells, a mouse L cel...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد علوم دارویی - پژوهشکده علوم 1392

purpose a metabolic abnormality such as obesity is a major obstacle in the maintenance of the human health system and causes various chronic diseases including type 2 diabetes, hypertension, cardiovascular diseases, as well as various cancers. this study was designed to summarize the recent scientific knowledge regarding the anti-obesity role of curcumin (diferuloylmethane), which is isolated f...

Introduction: Arginine-phenylalanine-amide-related peptide-3 (RFRP-3) is an inhibitor of gonadotropin releasing hormone (GnRH) secretion and an appetizer. Kisspeptin is a stimulator of GnRH and a regulator of energy metabolism. The objectives of the present study were to compare the effect of long term malnutrition on expression of RFRP-3 mRNA in dorsomedial hypothalamic nucleus (DMH) and Ki...

جعفرزاده, پرستو, عابدین زاده, محمود, قربانی, احمد, محسنی مهران, سید محمد, مولادوست, حسن, نورس فرد, محمدرضا,

Background and purpose: Airway stenosis is one the most dangerous diseases. Anethum graveolens L.(Dill) has anti-spastic effect on smooth muscle. The aim of this study was to investigate the effect of the hydroalcoholic extract of this plant on male rat tracheal smooth muscle contractile activity. Materials and methods: In this experimental study, tracheas of healthy rats were dissected. We in...

Journal: :The American journal of physiology 1999
Edwin K Jackson William A Herzer

Intrarenal artery infusions of low-dose human, but not mouse, leptin cause diuresis/natriuresis in rats [E. K. Jackson and P. Li. Am. J. Physiol. 272 ( Renal Physiol. 41): F333-F338, 1997]. The lack of effect of mouse leptin in the rat could be due to slight differences in the primary structure of mouse vs. rat leptin. To test this hypothesis, we infused single doses of rat (0.1, 0.3, 1, or 3 μ...

2016
Abdul Rehman Khan Fazli Rabbi Awan

CONTEXT Under normal physiological conditions, leptin regulates body weight by creating a balance between food intake and energy expenditure. However, in obesity, serum leptin levels increase and become defective to retain energy balance. EVIDENCE ACQUISITION Elevated serum leptin levels are regarded as an established marker of obesity. It is also reported that obese asthmatic patients have m...

Journal: :Circulation research 2001
F Parhami Y Tintut A Ballard A M Fogelman L L Demer

Leptin, the product of the ob gene, regulates food intake, energy expenditure, and other physiological functions of the peripheral tissues. Leptin receptors have been identified in the hypothalamus and in extrahypothalamic tissues. Increased circulating leptin levels have been correlated with cardiovascular disease, obesity, aging, infection with bacterial lipopolysaccharide, and high-fat diets...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه ولی عصر (عج) - رفسنجان - دانشکده ادبیات، زبانهای خارجی و تاریخ 1393

the current thesis is composed in five chapters in the following fashion: chapter two encompasses the applied framework of the project in details; the methodology of carl gustav jung to explain the process of individuation, the major archetypes and their attributes and his techniques to assess the mind’s strata are all explained. moreover, the austrian psychoanalysts, heinz kohut’s models of a...

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