In recent years, there has been an increased focus on placing patients at the center of health care research and evaluating clinical care in order to improve their experience and ensure that research is both robust and of maximum value for the use of medicinal products, therapy, or health services. This paper provides an overview of patients' involvement in clinical research and service evaluat...

OBJECTIVES/HYPOTHESIS Facial palsy manifests a broad array of deficits affecting function, form, and psychological well-being. Assessment scales were introduced to standardize and document the features of facial palsy and to facilitate the exchange of information and comparison of outcomes. The aim of this study was to determine which assessment methodologies are currently employed by those inv...

Background and purpose - Fast-track protocols have been introduced worldwide to improve the recovery after total hip arthroplasty (THA). These protocols have reduced the length of hospital stay (LOS), and THA in an outpatient setting is also feasible. However, less is known regarding the first weeks after THA with fast track. We examined patients' experiences of the first 6 weeks after hospital...

Projection-based reduced order models (PROMs) have shown promise in representing the behavior of multiscale systems using a small set generalized (or latent) variables. Despite their success, PROMs can be susceptible to inaccuracies, even instabilities, due improper accounting interaction between resolved and unresolved scales system (known as closure problem). In current work, we interpret mul...

BACKGROUND The preferred surgical procedure for treating morbid obesity is debated. Patient-reported outcome measures (PROMs) are relevant for evaluation of the optimal bariatric procedure. METHODS A total of 113 patients with BMI from 50 to 60 were randomly assigned to standard (n = 57) or distal (n = 56) Roux-en-Y gastric bypass (RYGB). Validated PROMS questionnaires were completed at basel...

INTRODUCTION Assessing the consequences of chronic spontaneous/idiopathic urticaria (CSU) requires the evaluation of health-related quality of life (HRQoL) associated with the severity of CSU signs and symptoms. It is important to understand how signs, symptoms, and HRQoL change over time in CSU. Evidence is lacking on how closely changes in signs and symptoms of CSU are related to changes in H...

The presence of several nonlinear analog circuits and Micro-Electro-Mechanical (MEM) components in modern mixed signal System-on-Chips (SoC) makes the fully automatic synthesis and optimization of such systems an extremely challenging task. The research presented in this thesis concerns the development of techniques for generating Parameterized Reduced Order Models (PROMs) of nonlinear dynamica...

Objectives: This paper evaluates the usefulness of a set of PROMs data collected prospectively, in a relational database, over several years. The data were collected as part of routine practice, to audit patients undergoing shoulder surgery. Methods: Data, rendered anonymous, which included all upper limb surgical procedures and all outcome questionnaires (including Oxford Shoulder Score, OSS) ...

OBJECTIVES To identify patient-reported outcome measures (PROMs) that have been developed and/or used with patients undergoing hip or knee replacement surgery and to provide a shortlist of the most promising generic and condition-specific instruments. METHODS A systematic review of the literature was performed to identify measures used in patients undergoing hip and knee replacement and extra...

BACKGROUND DEMQOL and DEMQOL-Proxy are widely used patient reported outcome measures (PROMs) of health related quality of life in people with dementia (PWD). Growing interest in routine use of PROMs in health care calls for more robust instruments that are potentially fit for reliable and valid comparisons at the micro-level (patients) and meso-level (clinics, hospitals, care homes). METHODS ...