نتایج جستجو برای: proline dehydrogenase prodh

تعداد نتایج: 87736  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1992
C A Hu A J Delauney D P Verma

Many plants synthesize and accumulate proline in response to osmotic stress. Despite the importance of this pathway, however, the exact metabolic route and enzymes involved in the synthesis of proline in plants have not been unequivocally identified. We report here the isolation of a mothbean (Vigna aconitifolia) cDNA clone encoding a bifunctional enzyme, delta 1-pyrroline-5-carboxylate synthet...

Journal: :Molecular cancer research : MCR 2015
Che-Pei Kung Sakina Khaku Matthew Jennis Yan Zhou Maureen E Murphy

UNLABELLED The tumor-suppressor protein p53, encoded by TP53, inhibits tumorigenesis by inducing cell-cycle arrest, senescence, and apoptosis. Several genetic polymorphisms exist in TP53, including a proline to arginine variant at amino acid 72 (P72 and R72, respectively); this polymorphism alters p53 function. In general, the P72 variant shows increased ability to induce cell-cycle arrest, whe...

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