نتایج جستجو برای: proliferation
تعداد نتایج: 182155 فیلتر نتایج به سال:
Background & Aims: Hepatocellular carcinoma remains often refractory to classic therapies. Therefore, the search for new natural compounds with minimal toxicity is of particular interest in treatment of liver cancer. In this context, it has been shown that 2-methyl-3-pentyl-6-methoxyprodiginine isolated from cell wall of Serratia marcescens has powerful growth inhibitory effects against di...
The cytotoxic chloroform fraction of Euphorbia aellenii afforded two cycloartane type triterpenes — cycloart-25-en-3,24-diol (1) and 24-methylene-cycloartan-3-ol (2) — for the first time from this plant. Preparation of cycloartane derivatives, 3, 24-O-diacetyl-cycloart-25-en as compound 3 and 3-O-acetyl-24-methylene-cycloartan (4) were conducted by acetylating of 1 and 2, respectively. The ...
Ferulago W. Koch. (Apiaceae) genus is represented by approximately 50 taxa throughout the world. Ferulago species are known as “Çakşır” or “Çağşır” in Turkey and mostly known for their aphrodisiac effects. However recent reports emphasize the activity of various Ferulago species against cancer, as well. The aim of this study was to investigate the effect of lyophilized extract of F. mughlea Peş...
UCB-1 (Pistacia atlantica × P. integrima) is a commercial rootstock for pistachio in some pistachio plantations across the world. This rootstock is very new in Iran and recently, it has been used commercially in some plantations due to its high growth. Propagation of this rootstock by tissue culture results in many limitations such as shoot tip necrosis (STN) and a low proliferation rate. There...
Background and Objective: Apoptosis is a form of programmed cell death and oxidative stress is one of the factors that lead to apoptosis. Ghrelin is a 28 amino acid peptide and its antiapoptotic effects have been shown previously. The aim of this study was to evaluate the effect of ghrelin on cell survival and apoptosis of rat bone marrow mesenchymal stem cells (BMSCs). Materials and Methods: ...
Background: Probiotic microorganisms are living normal flora of human body that have nutritional value and health benefits when administered in adequate amounts. The health benefits include prevention of bacterial diarrhea, skin eczema and recently understood, prevention and control of various cancers, as well. Different mechanisms such as stimulating the immune system, modifying the compositio...
Background and Aim: Previous studies have shown that some dyes used in photodynamic therapy (PDT) have a low pH and may cause root demineralization and remove the smear layer. This study aimed to assess and compare the effects of root biomodification with citric acid and PDT on the adhesion and proliferation of human gingival fibroblasts (HGFs). Materials and Methods: In this in vitro experime...
مقدمه: به دلیل تشخیص دیر هنگام سرطان تخمدان و عدم شیوه های درمانی موثر، این بیماری از نظر تلفات در بین سرطان های زنان بیشترین مرگ و میر را داراست. مطالعات نشان می دهد که برای دستیابی به روش های موثر برای تشخیص زود هنگام بیماری، جلوگیری از متاستاز و نیز درمان غیر تهاجمی این نوع سرطان، نیاز به شناخت وقایع مولکولی درون و برون سلولی است. مطالعه قبلی ما نشان داد که ژن sort1 در هر دو سطح ژن و پروتئین...
The ethyl acetate partition of dried methanolic extract of aerial parts of Euphorbia microsciadia (Euphorbiaceae) afforded three pentacyclic triterpenes, betulinic acid (1) from lupane type, oleanolic acid (2) from oleane type and ursolic acid (3) from ursane type triterpenes that are reported for the first time in this plant. These three compounds were structurally compared through their mass ...
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