نتایج جستجو برای: programmed cell death 1 ligand 2 protein

تعداد نتایج: 5723882  

2009
Sandra I. Aguiar Francisco R. Pinto Sónia Nunes Isa Serrano José Melo Raquel Sá-Leão Mário Ramirez Hermínia de Lencastre

2014
Yang Zhang Lei Wang Yuan Li Yunjian Pan Rui Wang Haichuan Hu Hang Li Xiaoyang Luo Ting Ye Yihua Sun Haiquan Chen

BACKGROUND The clinicopathologic characteristics of tumors expressing programmed death (PD-1) ligands (PD-Ls) PD-L1 or PD-L2 and their associations with common driver mutations in lung adenocarcinoma are not clearly defined, despite the progression of anti-PD-1/PD-L1 immunotherapy. METHODS PD-L1 and PD-L2 expression was measured by immunohistochemistry in 143 surgically resected lung adenocar...

2016

Historically, lung cancer was long considered a poorly immunogenic malignancy. In recent years, however, immune checkpoint inhibitors have emerged as promising therapeutic agents in non-small cell lung cancer(NSCLC). To date, the best characterized and most therapeutically relevant immune checkpoints have been cytotoxic Tlymphocyte-associated antigen 4 (CTLA-4), and the programmed cell death pr...

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