background: cerebral venous-sinus thrombosis is an uncommon form but important cause of stroke, especially in young-aged women. methods: we performed a retrospective descriptive-analytical study in which 124 patients with cerebral venous-sinus thrombosis, who referred to nemazee hospital, shiraz university of medical sciences from january 2000 to march 2008, were included, and their demographic...

background: gastric and colorectal adenocarcinoma are the second and the fifth most common cancers in iran, respectively. expression of cytokeratin 7 (ck7) is established in most malignancies including gastric and colorectal adenocarcinoma. demonstration of ck7 could be related to prognostic factors and help to the better management of the patients. the objective of our study was to evaluate th...

Background: Thyroid transcription factor-1 (TTF-1) is expressed in approximately 70% of lung adenocarcinomas and one the most reliable makers to distinguish primary adenocarcinoma from metastatic disease. TTF-1-negative status a poor prognostic factor, associated with efficacy immune checkpoint inhibitor (ICI) monotherapy. However, relationship between TTF-1 expression ICI plus chemotherapy sti...

BACKGROUND Systemic anaplastic large cell lymphoma (S-ALCL) is a rare disease with a highly variable prognosis and no standard chemotherapy regimen. Anaplastic lymphoma kinase (ALK) has been reported as an important prognostic factor correlated with S-ALCL in many but not all studies. In our study, we retrospectively analyzed 92 patients with S-ALCL from the Peking University Lymphoma Center fo...

Endotoxaemia and circulating tumour necrosis factor are important prognostic factors in severe sepsis and are implicated in the pathogenesis of septic shock. Because clinical and pathological features in acute pancreatitis are similar to septic shock this study sought to determine whether endotoxin and tumour necrosis factor were prognostic factors in 38 patients with prognostically severe acut...