OBJECTIVE To perform a pilot study of the effects on the breast by low-dose intrauterine progestogen combined with estrogen. DESIGN A prospective pilot study. SETTING University hospital. PATIENT(S) Twenty postmenopausal women without any previous breast disorder. INTERVENTION(S) Women were treated with a low-dose intrauterine system releasing 20 microg/24 hours of levonorgestrel in con...

Reproductive depression is the depression in women that is related to the hormonal changes of the menstrual cycle, pregnancy and the menopause and is manifested clinically as premenstrual depression, postnatal depression and climacteric depression. These three components occur in the same vulnerable women in that a woman with depression in the menopausal transition will usually have a history o...

Objective: Assessment of preoperative and postoperative outcomes of patients that were performed hysterescopic intrauterine adhesiolysis. Material and method: We reviewed 24 patients that underwent hysterescopy with the complaints of amenorrhea, hypomenorrhea, recurrent pregnancy loss between 2004-2008. The most complaints of patients were infertilty amenorrhea. Results: Adhesions occurs mainly...

Objectives: The aim of the multicenter, open-label, post-marketing, observational survey was to assess doctors’ preferences in choosing progestogen component combined contraceptive pill (CCP) and factors affecting this choice daily clinical practice as well non-contraceptive reasons use CCP containing drospirenone (CCPD) patients’ tolerance satisfaction with treatment. Material methods: This pe...

OBJECTIVE To assess the risk of venous thrombosis in current users of different types of hormonal contraception, focusing on regimen, oestrogen dose, type of progestogen, and route of administration. DESIGN National cohort study. SETTING Denmark, 1995-2005. PARTICIPANTS Danish women aged 15-49 with no history of cardiovascular or malignant disease. MAIN OUTCOME MEASURES Adjusted rate ra...

Emergency contraception (EC) has come a long way since the days when Family Planning clinics and other services provided cut-up sections of pink oral contraceptive pill strips and a dose or two of an antiemetic in tiny sealed plastic bags to women who were lucky enough to know about this option. When evidence demonstrated the superiority of the progestogen-only regimen in 1998 1 , these plastic...

During the past 5 years, a number of important advances have been made in our understanding of the mechanisms of sex steroid-induced breakthrough bleeding (BTB). These observations suggest that superficial endometrial vascular fragility may be the mechanism underlying BTB, and molecular changes in the microvasculature as well as hysteroscopic observations have supported this hypothesis. This pa...