We examine heritability estimation of an ordinal trait for osteoarthritis, using a population of pig-tailed macaques from the Washington National Primate Research Center (WaNPRC). This estimation is non-trivial, as the data consist of ordinal measurements on 16 intervertebral spaces throughout each macaque's spinal cord, with many missing values. We examine the resulting heritability estimates ...

Mortality hazard and length of time until death are widely used as health outcome measures and are themselves of fundamental demographic interest. Considerable research has asked whether labor force retirement reduces subsequent health and its mortality measures. Previous studies have reported positive, negative, and null effects of retirement on subsequent longevity and mortality hazard, but i...

In the present paper a mixed approach is proposed for the simultaneously estimation of regression and correlation structure parameters in multivariate probit models using generalized estimating equations for the former and pseudo-score equations for the latter. The nite sample properties of the corresponding estimators are compared to estimators proposed by Qu, Williams, Beck and Medendorp (199...

The nonlinear fixed-effects model has two shortcomings, one practical and one methodological. The practical obstacle relates to the difficulty of computing the MLE of the coefficients of non-linear models with possibly thousands of dummy variable coefficients. In fact, in many models of interest to practitioners, computing the MLE of the parameters of fixed effects model is feasible even in pan...

In regression applications with categorical predictors, interest often focuses on comparing the null hypothesis of homogeneity to an ordered alternative. This article proposes a Bayesian approach for addressing this problem in the setting of normal linear and probit regression models. The regression coefficients are assigned a conditionally conjugate prior density consisting of mixtures of poin...

Statistics ANOVA and related Multiple imputation Basic statistics Multivariate analysis of variance and Binary outcomes related techniques Categorical outcomes Nonlinear regression Censored and truncated regression models Nonparametric statistics Cluster analysis Ordinal outcomes Correspondence analysis Other statistics Count outcomes Pharmacokinetic statistics Discriminant analysis Power and s...

The inability of farmers to comply with essential precautions in the course of spraying agrochemicals remains a policy dilemma, especially in developing countries. The objectives of this paper were to assess compliance of cocoa farmers with agrochemical safety measures, analyse the factors explaining involvement of cocoa farmers in the practice of reusing agrochemical containers and wearing of ...

Innovation, in all its forms, has become a central activity companies. Moreover, innovation is considered as the engine of growth several countries. The main objective this paper to study determinants (product and process) firms Middle East North Africa (MENA) region via concentrating on impact financial non-financial obstacles. empirical refers row data collected by World Bank’s Survey E...

PURPOSE To estimate the critical duration of temporal summation for achromatic Goldmann III stimuli under the conditions of standard automated perimetry (SAP) and quantify response variability for short-duration stimuli. METHODS Contrast thresholds were gathered using the method of constant stimuli for seven circular (0.48° diameter) incremental stimuli of varying duration (sum-of-frames equi...