In this paper, we investigate the temperature and pH dependence of the mitochondrial inner membrane anion channel (IMAC) that is believed to be involved in mitochondrial volume homeostasis. At pH 7. 4, the flux of malonate is highly temperature-dependent with rates increasing from 1 nmol/min mg at 5 degrees C to 1900 nmol/min mg at 45 degrees C. The Arrhenius plot is nonlinear with the activati...

A plot of the correlation function of a given DNA sequence has certain characteristic features common to almost all organisms. One common feature is that the correlation values at distances that are multiples of three is higher than correlation values at other distances. Because of this such a correlation plot can be divided into two or three curves with different scalings. P. falciparum has a ...

This study has conducted to find the effects of trade deficit on the economy of Pakistan in which trade deficit is the independent and gross domestic product, foreign direct investment exchange rate are the dependent variables. Depending on the availability of data we have selected the longest possible sample period to avoid the small sample bias. A sample period of 24 years has been selected f...

While in the univariate case solutions of linear recurrences with constant coe cients have rational generating functions we show that the multivariate case is much richer even though initial conditions have rational generating functions the corresponding solutions can have generating functions which are algebraic but not rational D nite but not algebraic and even non D nite Introduction The aim...

the aij and bij being real or complex. This vector field is a deformation of the vector field x∂y −y∂x whose trajectories are concentric circles around 0. We prove in this paper a precise version of the following assertion: for any compact K in the space of the (aij ,bij ), there exist a number p(q) and a neighborhood U(q,K) of 0 such that for (a,b) ∈ K , either 0 is again a center of Wa,b (i.e...

Bousquet-Mélou and Petkovšek investigated the generating functions of multivariate linear recurrences with constant coefficients. We will give a reinterpretation of their theory by means of division theorems for formal power series, which clarifies the structural background and provides short, conceptual proofs. In addition, extending the division to the context of differential operators, the c...

Orthogonal polynomials on the unit circle are completely determined by their reflection coefficients through the Szegő recurrences. We assume that the reflection coefficients tend to some complex number a with 0 < |a| < 1. The orthogonality measure μ then lives essentially on the arc {e : α ≤ t ≤ 2π − α} where sin α 2 def = |a| with α ∈ (0, π). Under the certain rate of convergence it was prove...

p(t | x) t x x x = 0.8 = 0.5 = 0.2 Figure 7: Plot of the conditional probability densities of the target data, for various values of x, obtained by taking vertical slices through the contours in Figure 6, for x = 0:2, x = 0:5 and x = 0:8. It is clear that the Mixture Density Network is able to capture correctly the multimodal nature of the target data density function at intermediate values of ...

Over the last few years, miRNA microarray platforms have provided great insights into the biological mechanisms underlying the onset and development of several diseases. However, only a few studies have evaluated the concordance between different microarray platforms using methods that took into account measurement error in the data. In this work, we propose the use of a modified version of the...