In recent years the use of pulsed radiofrequency (PRF) to treat chronic pain conditions has generated intense interest in the pain community. PRF is a minimally invasive, target-selective technique that has reported anecdotal benefit at reducing post-amputation stump pain (1), chronic radicular/ganglion pain (2), neuropathic pain (3), and arthropathic pain (4). There is no published data on usi...

Programmed -1 ribosomal frameshifting (-1 PRF) is a widely used translational mechanism facilitating the expression of two polypeptides from a single mRNA. Commonly, the ribosome interacts with an mRNA secondary structure that promotes -1 frameshifting on a homopolymeric slippery sequence. Recently, we described an unusual -2 frameshifting (-2 PRF) signal directing efficient expression of a tra...

Title of Document: mRNA SUICIDE: DESTABILIZATION BY PROGRAMMED RIBOSOMAL FRAMESHIFTING Jonathan L. Jacobs, Ph.D., 2006 Directed By: Associate Professor Jonathan D. Dinman, Department of Cell Biology & Molecular Biology Cis-acting mRNA elements that promote programmed -1 ribosomal frameshifting (-1 PRF) redirect a fraction of translating ribosomes into a new translational reading frame. In virus...

BACKGROUND The purpose of this study was to create biomaterial scaffolds like platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) containing stromal cell-derived factor-1 (SDF1) as a chemokine to induce hyaline cartilage regeneration of rabbit knee in a full thickness defect. METHODS We created a full thickness defect in the trochlear groove of thirty-six bilateral knees of eighteen mat...

In this paper, we first present the principles of STAP and discuss the properties of optimum detector, as well as problems associated with estimating the adaptive weights such as ambiguities and the high computational cost. The performances are evaluated highlighting the influence of radar parameters on the detection of slow targets. To resolve problem of high computational cost of optimal STAP...

Resistance to bacterial speck disease in tomato (Solanum lycopersicum) is activated upon recognition by the host Pto kinase of either one of two sequence-unrelated effector proteins, AvrPto or AvrPtoB, from Pseudomonas syringae pv tomato (Pst). Pto induces Pst immunity by acting in concert with the Prf protein. The recently reported structure of the AvrPto-Pto complex revealed that interaction ...

The main purpose of this study is to perform numerical simulation of nanofluids as the coolant in VVER-440 fuel rod bundle. The fuel rod bundle contains 60 fuel rods with length of 960 mm and 4 spacer grids. In VVER-440 fuel rod bundle the coolant fluid (water) is in high pressure and temperature condition. In the present Thermo-hydraulic simulation, water-AL2O3 nanofluids containing various vo...

1n this program,aresearchgasturbinecombustor is used to study the influence of individual variables (in particular, fuel spray characteristics) on primary zone emissions. The unique combustor is operated under realistic conditions and allows for independent control of drop size, fuel-air ratio, air inlet temperature, pressure, reference velocity, and residence time. Also, it lends itself to the...

In order to solve energy crisis, the search for alternative fuel is extensively important. Alternative fuels selected should be renewable, sustainable and eco-friendly. In India, kerosene is also used as a fuel in cooking stove. Kerosene contains impurities like sulphur, aromatics and hydrocarbons, which causes environmental degradation. In this experimental investigation, blends of ethanol and...

Fuel maps are essential for computing spatial fire hazard and risk and simulating fire growth and intensity across a landscape. However, fuel mapping is an extremely difficult and complex process requiring expertise in remotely sensed image classification, fire behavior, fuels modeling, ecology, and geographical information systems (GIS). This paper first presents the challenges of mapping fuel...