Understanding immunodominance, the phenomenon of epitope-specific T cells expanding in an often distinctly hierarchical fashion, is important for the design of T-cell-based intervention strategies. Several recent studies have investigated immunodominance of H-2D(b)-restricted CD8(+) T cells specific for the nucleoprotein NP366 and acid polymerase PA224 epitopes during influenza A virus infectio...

A hydatid cyst is a zoonotic infection caused by the larval forms of mostly the Echinococcus granulosus. In humans, the most common site of cyst development is the liver (60%), followed by the lungs (20%), and much less commonly in other organs such as kidney, spleen, brain, and other soft tissues. The localization of cysts in muscles and subcutaneous is very rare. We report a case of 38-year-o...

OBJECTIVE To compare the effectiveness of additional moxibustion at point BL67 with moxibustion at a non-specific acupuncture point and with usual care alone to correct non-vertex presentation. METHODS This was a multicentre randomised controlled trial in which 406 low-risk pregnant women with a fetus in ultrasound breech presentation, with a gestational age of 33-35 weeks, were assigned to (...

Basal cell carcinoma (BCC) is the commonest cancer in Caucasians. Its incidence is rising and many patients develop multiple primary tumours at separate sites. Factors determining time between first primary tumour presentation and the next new primary lesion are unclear. We used Cox's proportional hazards model to study, in 856 Caucasians, the influence of tumour site, individual characteristic...

primary malignant neoplasms of the pericardium are rare and are predominantly mesotheliomas, followed by benign localized fibrous mesothelioma, malignant fibrosarcoma, angiosarcoma and benign and malignant teratomas. 1 this article concerns an atypical presentation of this malignant tumor with symptoms and signs of pericardial effusion. this unusual feature was complete encasement of the heart ...

BACKGROUND AND AIM: Squamous cell carcinoma (SCC) is usually considered a disease of older people. Recently, there is a change in the occurrence of such lesions in young patients and lacking the established risk factors. CASE REPORT: A 21-year-old male reported with an innocuous gingival growth over lower incisors since a month. Within 15 days he noticed another gingival growth in same region l...

Thyroid ectopia is a dysgenesis of thyroid gland and Lingual position represents the most frequent ectopic location accounting up to 90% of ectopic cases. Hypothyroidism is commonly present because of absence of a normal thyroid gland in most instances. Primary hypothyroidism in juvenile population generally leads to retardation of linear growth and delay or even arrested puberty. We present a ...

primary pancreatic lymphoma is a rare extranodal manifestation of any histopathologic subtype of b cell non-hodgkin's lymphoma that predominantly involves the pancreas. it comprises less than 0.2% of pancreatic malignancies and less than 0.7% of non-hodgkin's lymphomas. this lymphoma is almost never suspected clinically. it is usually diagnosed by surgical exploration for suspected ad...