“I could not stop crying when my doctor told me I was in menopause! I was only 32 years old and married less than year ago! I wondered whether I had done anything wrong. Later I found out that my grandmother, mother and my aunt went through menopause when they were in their 30’s, but we had never talked about these things before. I never expected this would happen to me because everyone in my f...

BACKGROUND Polycystic ovary syndrome (PCOS) is a very common disorder well known to be associated with insulin resistance and metabolic disease. Insulin resistance is likely involved in the promotion of the PCOS reproductive phenotype and may mediate some of the ovarian morphology seen in the disorder. The phenotype of each individual woman with PCOS can vary widely as can her metabolic risk. ...

Ovarian microcystic stromal tumors (MCSTs) and ovarian primary solid pseudopapillairy neoplasms (SPNs) are rare ovarian tumors, and recently classified as distinctive variant in the stromal category and miscellaneous tumors respectically in 2009 and 2010. Ever since, there were less then 10 MCSTs and ovarian primary SPNs reported in English literatures. Both of them had something in common, inc...

Involvement of the ovary by malignant lymphoma is well known as a late manifestation of disseminated disease. However, primary ovarian lymphoma (POL) is rare, accounting for 0.5 % of all non-Hodgkin’s lymphoma and 1.5 % of all ovarian neoplasms [1]. We present a case of ovarian non-Hodgkin’s lymphoma, manifesting like an advanced ovarian cancer, which was managed by surgery and chemotherapy (Fi...

BACKGROUND Neuroendocine carcinoma of the gynecologic tract is rare and poses a significant clinical challenge because of tumor heterogeneity and lack of standardized guidelines for treatment. Ovotestis refers to the histology of a gonad that contains both ovarian follicles and testicular tubular elements. Ovotesticular disorder of sexual development occurs in fewer than 10% of all disorders of...

Background: To determine the effect of ovarian stimulation on the height of the epithelial cells of fallopian tubes and development of ovarian follicles and corpus luteum in NMRI mice. Materials and Methods: Forty female NMRI mice of 6 to 8 weeks were selected and divided into 4 groups: control group, 10 mice that were injected with saline. The second group of 10 mice that were injected with 7 ...

Polycystic ovarian syndrome (PCOS) is sometimes called Stein-Leventhal Syndrome after the two doctors who first described it in 1935. 1 It is the most common ovarian disorder with typical features of obesity, anovulation, hyperandrogenism, hirsutism and infertility. The accepted nomenclature for the syndrome is PCOS, despite the fact that polycystic ovaries are non-specific findings and can occ...

Difficulties in the detection, diagnosis, and treatment of ovarian cancer result in an overall low survival rate of women with this disease. A better understanding of the pathways involved in ovarian tumorigenesis will likely provide new targets for early and effective intervention. Here, we have used serial analysis of gene expression (SAGE) to generate global gene expression profiles from var...

Ovary is one of the main endocrine glands, also the source of female fertility and at the same time the organ with the largest number of histological varieties of malignant tumors. The most frequent among primary neoplasms are epithelial tumors. Secondary tumors of the ovary arise by direct tumor extension from adjacent organs or tissues, by transtubal or transperitoneal route, as well as hemat...