نتایج جستجو برای: primary gastric adenocarcinoma

تعداد نتایج: 790721  

2017
Luguang Liu Hongbo Hao Lijuan Zhao Junxia Hu Baocai Si

This study investigated the survival and prognosis of 298 gastric adenocarcinoma patients with no distant metastasis. For analysis and comparison of the prognosis of patients, a retrospective analysis was performed in 298 patients with perfect clinical data and follow-up data who received the D2 resections for gastric cancer in Shandong Provincial Hospital Affiliated to Shandong University betw...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2004
Willem A Marsman Rakesh S Birjmohun Bastiaan P van Rees Eric Caspers G Johan A Offerhaus Piter J Bosma J Jan B van Lanschot

PURPOSE Adenocarcinomas of the distal esophagus and gastric cardia are two tumors that have many features in common. They have similar prognoses, treatment modalities, and patterns of dissemination. The etiology is different, with gastroesophageal reflux disease playing a major role for esophageal adenocarcinoma, in contrast to adenocarcinoma of the gastric cardia. In the present study, we inve...

2015
ZHIMING WU LIN ZHANG NAN LI LINA SHA KUNPENG ZHANG

Thioredoxin domain-containing 5 (TXNDC5) is overexpressed in a number of human carcinomas. However, the involvement of TXNDC5 in gastric adenocarcinoma remains unclear. In the present study, the immunohistochemical expression and clinicopathological significance of TXNDC5 in gastric adenocarcinoma was investigated. The immunohistochemical expression of TXNDC5 was detected in 54 gastric adenocar...

Journal: :Genetics and molecular research : GMR 2015
H Wei H Q Gao H B Li S J Qi W L Liu L Xu H Li J X Liu Z M Dong

The aim of this study was to characterize variations in Raf kinase inhibitor protein (RKIP) expression and related signaling molecules in gastric cardia adenocarcinoma. Cancerous and precancerous tissues were collected from patients with gastric cardia adenocarcinoma and normal tissue was collected from healthy controls. RKIP expression was detected in these tissues and the serum levels of NF-κ...

2017
Altin Malaj Fatmir Bilaj Albana Shahini Marjeta Miraka

AIM OF THE STUDY Gastric adenocarcinoma is among most frequent among cancers in Albania. Early detection and staging is helped by imaging methods, including CT and MRI. This study provides evidence on the CT and MRI accuracy in detecting and pre-operative staging of gastric adenocarcinoma in 62 patients in a diagnostic clinic in Albania. The correct staging of the gastric adenocarcinoma helps d...

Journal: :Gut 2003
A O-O Chan S-K Lam B C-Y Wong W-M Wong M-F Yuen Y-H Yeung W-M Hui A Rashid Y-L Kwong

BACKGROUND E-cadherin is an adhesion molecule involved in tumour invasion/metastasis. Silencing of E-cadherin by promoter CpG methylation has been shown in both familial and sporadic gastric cancers. Helicobacter pylori is a class I carcinogen in gastric cancer. AIMS This study was undertaken to investigate the association between methylation of E-cadherin and H pylori in gastric mucosa from ...

2003
C-Y Wong W-M Wong M-F Yuen Y-H Yeung W-M Hui A Rashid Y-L Kwong

Background: E-cadherin is an adhesion molecule involved in tumour invasion/metastasis. Silencing of E-cadherin by promoter CpG methylation has been shown in both familial and sporadic gastric cancers. Helicobacter pylori is a class I carcinogen in gastric cancer. Aims: This study was undertaken to investigate the association between methylation of E-cadherin and H pylori in gastric mucosa from ...

2015
Muhammad Miftahussurur Rabi Prakash Sharma Pradeep Krishna Shrestha Ramesh Kumar Maharjan Seiji Shiota Tomohisa Uchida Hiroki Sato Yoshio Yamaoka

The sequence of events in the gastric mucosa that precede the manifestation of gastric cancer has been shown to begin decades earlier. Typically, it begins with chronic non-atrophic gastritis that progresses to chronic atrophic gastritis, which may eventually lead to intestinal metaplasia, dysplasia, and finally adenocarcinoma (Kuipers, 1999). Helicobacter pylori infection is accepted as the pr...

Journal: :GE Portuguese Journal of Gastroenterology 2022

Gastric adenocarcinoma is one of the most frequent and deadly cancers worldwide. However, its incidence variable, being higher in eastern countries where screening general population recommended. On other hand, low to intermediate-risk countries, may not be cost-effective, therefore, it necessary aware high-risk populations that benefit from adequate surveillance. It always easy identify these ...

2018
Lei Cai Yan Li Xue-wen Yang Xiao Lian Man Guo Shu-ao Xiao Wen-bin Wang Hong-wei Zhang

Background The mucinous component is a special histologic factor in gastric adenocarcinoma. The aim of this study was to assess the prognostic significance of mucinous component in gastric adenocarcinoma according to proportion. Patients and methods Candidate patients with gastric adenocarcinoma were given radical D2 gastrectomies from September 2008 to May 2015 in our division. Clinicopathol...

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