Background Diagnosis of food allergy relies on clinical history, tests for allergen specific IgE and oral food challenges. A recent reaction consistent with IgE-mediated symptoms in conjunction with a positive allergen-specific IgE test (either skin prick test (SPT) or serum allergen specific IgE (sIgE)) is usually sufficient to diagnose food allergy. In the absence of a reaction history, a pos...

Topical corticosteroids are frequently recognised as a cause of allergic contact dermatitis but in only few cases the administration of intranasal corticosteroids has been reported as the cause of systemic allergic reaction.1--6 A 34-year-old non-atopic woman started treatment with nasal budesonide for a common cold. On the second day of treatment the patient developed, 8 h after the administra...

Background: The role of food allergy in atopic dermatitis (AD) is controversial. The aim of this study was to determine the frequency of food allergens in children with AD. Method: Fifty one atopic dermatitis children aged 6 months to 5 years entered our study. The severity of AD was determined by scoring index of AD (SCORAD). Skin prick test (SPT) was done using 15 allergens including the whit...

BACKGROUND Hypersensitivity reactions to metronidazole are infrequently described. However, we believe that such reactions are increasing due to growing use of the drug for the treatment of amebiasis and anaerobe infections combined with other antibiotics. The present study assesses the need for oral provocation in patients with probable hypersensitivity reactions to metronidazole. METHODS We...

the prevalence of allergic diseases is high in the general population, and the high prevalence of these diseases not only leads to considerable mortality and morbidity, but also has economic importance. in this study 400 patients were evaluated in tehran and karaj cities during 1995-1998. skin prick test with stan¬dard extracts was done in patients in comparison with controls. selection of ex¬t...

BACKGROUND Less than 10% of pancreatic cancer cases survive 5 years, yet its etiology is not well understood. Studies suggest allergies are associated with reduced pancreatic cancer risk. Our study collected additional information on allergies (including skin prick test results and differentiation of allergic/nonallergic asthma), and is the first to assess possible confounding by allergy medica...

BACKGROUND Obstructive sleep apnoea syndrome is associated with significant morbidity. A high prevalence of obstructive sleep apnoea (OSA) symptoms has been reported in patients with asthma and chronic obstructive pulmonary disease (COPD). There are limited studies regarding relationship between atopy and OSA. OBJECTIVE To study the risk of obstructive sleep apnoea among middle aged chronic o...

Background: Atopic dermatitis is a major public health problem, often starting in early childhood and sometimes followed by other allergic diseases. Although hypersensitivity to foods is assumed to play an essential role in the development of atopic dermatitis in some patients, little is known about common food allergens in Iranian children with atopic dermatitis. Objectives: This study was des...

OBJECTIVE To measure the incidence of platinum salt sensitivity (PSS) in refinery workers and examine the influence of cigarette smoking and exposure to platinum salts on sensitisation. DESIGN A prospective cohort study with examination of workers at quarterly intervals for 18 months, and again at 24 months. SETTING A South African primary platinum refinery. SUBJECTS 78 new recruits, sele...

Accepted 19 June 1995 Abstract Objective-To measure the incidence of platinum salt sensitivity (PSS) in refinery workers and examine the influence ofcigarette smoking and exposure to platinum salts on sensitisation. Design-A prospective cohort study with examination ofworkers at quarterly intervals for 18 months, and again at 24 months. Setting-A South African primary platinum refinery. Subject...