A. AGT as the substrate for renin B. AGT as a member of the serpin superfamily: other roles for AGT? IV. Tissue and Cellular Distribution V. Regulation A. Hormonal regulation of AGT B. Regulation of AGT in disease C. Regulation of AGT gene transcription VI. Molecular Genetics of AGT in Human Essential Hy-pertension A. Strategies B. Linkage studies C. Association studies of AGT polymorphism and ...

Managed pressure drilling is a sophisticated pressure control method which is intended to meet increasingly high demands in drilling operations in the oil and gas industry. With this method, the well is pressurized and the drilling mud is released through a control choke which can be used to actively control/reject pressure variations. Such a control system needs to handle several disturbances,...

OBJECTIVES Central and peripheral roles of nitric oxide (NO) in blood pressure regulation have been suggested. The present study was aimed at examining if the role of NO in blood pressure regulation is altered in chronic renal failure. METHODS Blood pressure responses to acute inhibition of NO were examined in 5/6 nephrectomized rats. Three weeks after the renal ablation, under thiopental (50...

Pressure balance control between steel sleeve fillings and stratum is the key to ensuring project safety in receiving construction of subway shield tunnels. Here, realize active regulation filing pressure sleeve, this study first improves fixed cover a conventional piston that can slide freely along longitudinal direction puts forward corresponding methods for hydraulic mechanical regulation. T...

In experimental obstructive chronic pancreatitis the normal hyperaemic response to secretory stimulation is lost, suggesting abnormal vascular regulation. Vascular regulatory mechanisms were investigated by observing the effect of increments in portal pressure on pancreatic blood flow in normal cats and cats with chronic pancreatitis. Normal cats maintained pancreatic blood flow until portal pr...

We studied the response of cerebral blood flow to acute step decreases in arterial blood pressure noninvasively and nonpharmacologically in 10 normal volunteers during normocapnia, hypocapnia, and hypercapnia. The step (approximately 20 mm Hg) was induced by rapidly deflating thigh blood pressure cuffs following a 2-minute inflation above systolic blood pressure. Instantaneous arterial blood pr...

BACKGROUND Elevated blood pressure is a risk factor for cardiovascular, cerebrovascular, and renal diseases. Complex mechanisms of blood pressure regulation pose a challenge to identifying genetic factors that influence interindividual blood pressure variation in the population at large. METHODS AND RESULTS We performed a genome-wide linkage analysis of systolic blood pressure in humans using...

BACKGROUND Coronary blood flow can always be matched to the metabolic demand of the myocardium due to the regulation of vasoactive segments. Myocardial compressive forces play an important role in determining coronary blood flow but its impact on flow regulation is still unknown. The purpose of this study was to develop a coronary specified flow regulation model, which can integrate myocardial ...

In experimental obstructive chronic pancreatitis the normal hyperaemic response to secretory stimulation is lost, suggesting abnormal vascular regulation. Vascular regulatory mechanisms were investigated by observing the effect of increments in portal pressure on pancreatic blood flow in normal cats and cats with chronic pancreatitis. Normal cats maintained pancreatic blood flow until portal pr...