OBJECTIVE Previous reports have suggested that disturbances in calcium regulation may underlie the pathophysiologic characteristics of premenstrual syndrome and that calcium supplementation may be an effective therapeutic approach. To evaluate the effect of calcium carbonate on the luteal and menstrual phases of the menstrual cycle in premenstrual syndrome, a prospective, randomized, double-bli...

It's much less common than premenstrual syndrome, but it can have a severe impact on your patient's quality of life. Here's how to recognize it and alleviate the symptoms.

Premenstrual symptoms are highly prevalent among women of reproductive age. Population-based studies suggest as much as 85%–90% of women regularly experience one or more physical, emotional, or behavioral symptoms before the onset of menses. For the majority of women, symptoms are relatively mild and do not adversely impact quality of life. For 15%–20% of women, symptoms are severe enough to im...

BACKGROUND A majority of women from all cultures and socioeconomic levels experience diverse psychosomatic and behavioral symptoms premenstrually, a phenomenon commonly termed premenstrual syndrome, although symptoms and discomfort levels vary from woman to woman. The underlying pathological mechanisms of premenstrual syndrome remain unknown; however, altered function or even slight disorder of...

Premenstrual symptoms are extremely common among women of reproductive age. As many as 75% of women report minor or isolated premenstrual symptoms, up to 50% of women are estimated to have premenstrual syndrome (PMS), and 3% to 5% of women are considered to have severe PMS or premenstrual dysphoric disorder (PMDD) [1,2]. PMDD has been defined as a psychophysiological disorder in which both soma...

PURPOSE The aim of this study was to investigate the frequency, associated factors, and management approaches of premenstrual dysphoric disorder (PMDD) and premenstrual syndrome (PMS) in Jordanian women. DESIGN AND METHODS Three hundred premenopausal women completed a self-administered questionnaire. FINDINGS Moderate-severe PMS was reported by 29% of women, while 14% had PMDD. Younger unma...

We studied 42 women with severe Premenstrual Tension Syndrome (PMTS) and compared their clinical features and adrenocortical function with those seen in major depressive disorders. Self-report scales demonstrated that PMTS was very distressing, but the disturbance did not meet the RDC for Major Depressive Disorder endogenous subtype. Twenty-four hour urinary free cortisol estimation did not ind...