PURPOSE To investigate whether allelic polymorphism of haptoglobin (Hp) is associated with premature rupture of membrane (PROM), the Hp phenotypes of pregnant women with PROM were analyzed. PATIENTS AND METHODS The Hp phenotypes of 221 pregnant Korean women (187 control and 34 PROM patients) were determined by benzidine/hydrogen peroxide staining, following native polyacrylamide gel electroph...

The premature rupture of membranes (PROM), defined as rupture of the amniotic membranes before the onset of labor, remains a serious challenge for obstetricians, because of its high rate of comorbidity, including infection, cesarean section, and other associated problems. Preterm PROM (PPROM) (occurring before the 37 full gestational weeks), accompanied by preterm birth, is the leading cause of...

BACKGROUND Premature rupture of membrane (PROM) is linked to significant maternal prenatal mortalities and morbidity. In Ethiopia, where maternal mortality is still high, the maternal and fetal outcomes in PROM is very important to decrease maternal and child mortality and for better management and prevention of complications. Thus, this study aimed to detect the maternal and fetal outcomes and...

There are studies in literature which have reported that the neutrophile to lymphocyte ratio (NLR) is associated with gestational diabetes, pre-eclampsia, severity of premature prelabour rupture membranes (PPROM) and hyperemesis gravidorum. may also be an association healthy pregnancies without any pathological conditions. The aim this study was investigate whether neutrophil/lymphocyte platele...

BACKGROUND: Our purpose was to determine whether AFI<5 cm after preterm premature rupture of the membranes (PPROM) is associated with an increased risk of perinatal morbidity. METHODS: We performed a prospective cohort study of 95 singleton pregnancies complicated by preterm premature rupture of the membranes (PPROM) with delivery between 26 and 34 weeks gestation.Patients were categorized in t...

OBJECTIVES While early-onset neonatal GBS sepsis is positively associated with premature birth and prolonged rupture of membranes, there is debate in the literature as to whether maternal GBS colonization is a predictor of adverse obstetric outcome. This is a critical issue to resolve for appropriate management (expectant vs. interventional management) of the patient presenting with premature r...