Asthma is considered to be the most common respiratory disorder complicating pregnancy. Seventy-six asthmatic and 152 non-asthmatic pregnant women were studied. Maternal asthma was significantly associated with adverse infant outcomes, including prematurity, low birth weight and the need for Cesarean delivery. The results of this study could indicate that pregnant women with asthma were at subs...

Background—Women with familial hypercholesterolemia (FH) are prone to early cardiovascular disease and death. It is unknown whether FH adversely affects pregnant women and birth outcomes. We determined whether heterozygous FH women are at higher risk of premature birth ( 37 gestational weeks), delivering children with low birth weight ( 2500 g) and/or with congenital malformations compared to w...

BACKGROUND Pregnancy has a huge impact on the thyroid function in both healthy women and those that have thyroid dysfunction. The prevalence of thyroid dysfunction in pregnant women is relatively high. OBJECTIVE The objective of this review was to increase awareness and to provide a review on adverse effect of thyroid dysfunction including hyperthyroidism, hypothyroidism and thyroid autoimmun...

BACKGROUND Women with schizophrenia are at increased risk for adverse pregnancy outcomes. It is not known whether offspring born to fathers with schizophrenia also have an increased risk. AIMS To evaluate paternal and maternal influences on the association between schizophrenia and pregnancy outcomes. METHOD A record linkage including 2 million births was made using Swedish population-based...

Pregnancy is associated with profound changes in sleep. Up to 75% of pregnant women experience some form of sleep disruption during pregnancy. The emerging data from recent years suggests that sleep disturbances may represent a novel contributor to adverse pregnancy outcomes and that sleep disorders during pregnancy may affect both maternal and fetal outcomes. In spite of the increased awarenes...

BACKGROUND It is relatively less known whether pre-pregnancy obesity and excess gestational weight gain (GWG) are associated with caesarean delivery, pregnancy complications, preterm birth, birth and placenta weights and increased length of postnatal hospital stay. METHODS We used a population-based cohort of 6632 women who gave birth in Brisbane, Australia, between 1981 and 1983. The indepen...

BACKGROUND The absence of robust evidence of safety of medicines in pregnancy, particularly those for major diseases provided by public health programmes in developing countries, has resulted in cautious recommendations on their use. We describe a protocol for a Pregnancy Registry adapted to resource-limited settings aimed at providing evidence on the safety of medicines in pregnancy. METHODS...

BACKGROUND Atosiban is administered to women undergoing in vitro fertilization-embryo transfer (IVF-ET) to improve pregnancy outcomes. However, the results of this treatment were controversial. We conducted this meta-analysis to investigate whether atosiban improves pregnancy outcomes in the women undergoing in vitro fertilization (IVF). METHODS Databases of PubMed, EMBASE, Web of Science, Ch...

OBJECTIVE In a study of Gullah African-Americans, we compared pregnancy outcomes before and after systemic lupus erythematosus (SLE) diagnosis to controls to test whether there is a predisease state that negativelyaffects pregnancy outcomes. DESIGN Cases and controls reporting at least one pregnancy were included. Controls were all Gullah African-American females. We collected demographic, so...