In an epidemiologic study of the total population of Tecumseh, Michigan, 98 deaths from coronary heart disease were observed between 1959 and 1965. Forty-five of the fatalities occurred within 1 hour of the onset of symptoms and were classified as sudden. The proportion of sudden deaths among men was nearly twice that among women, and the incidence increased progressively with age in both sexes...

PURPOSE OF REVIEW The purpose of this review is to summarize the evidence for the association between obesity and obstructive sleep apnea (OSA), as well as predisposing risk factors and treatment strategies for OSA amongst obese patients. RECENT FINDINGS Recent findings highlight a number of factors including sex, age, upper airway structure and ethnicity, which may predispose patients to OSA...

Recent data indicate a rise in obesity both in children and adolescents in developing countries. The overall prevalence of overweight/obesity in urban children in New Delhi has shown an increase from 16% in 2002 to about 24% in 2006-2007. Our recent data show that the prevalence among adolescent children was 29% in private schools and 11.3% in government funded schools. While India already has ...

Predisposing Factors in Cardiogenic Cerebral Embolism To the Editor: I read with interest the article by Yasaka and associates' on the pathophysiology of intracardiac thrombus formation in patients with recurrent cerebral embolism. However, I was surprised that there were no cases found or mention made of either paradoxical embolism or atrial septal aneurysm as predisposing factors of recurrent...

In a prospective study of cytomegalovirus (CMV) infection in pregnancy 69 congenitally infected infants were identified. The age, race, marital status, social class, and parity of the mothers of congenital CMV infants were compared with those of the screened population of women with non-infected infants. These factors were all individually strongly associated with the prevalence of congenital C...

Heatstroke is a common veterinary emergency that, depending on the severity of injury, can progress to a life-threatening condition. Heatstroke can be classic (nonexertional) or exertional. Classic heatstroke develops when the body is exposed to high external temperatures, whereas exertional heatstroke is caused by strenuous exercise. Thermoregulation is the intrinsic ability of the body to mai...

The etiology of localized scleroderma remains unclear. The objective of this article is to review different theories of etiology, specifically provocative and predisposing factors for the development of localized scleroderma. The mini-review presents the factors, which may influence the occurrence of localized scleroderma. The genetic predisposition for the development of scleroderma is a relev...

Background: Patients with rheumatoid arthritis (RA) and obesity have a lower risk of early death than patients normal weight due to the so-called “obesity paradox”. Available publications discuss three phenotypes obesity: classical obesity, metabolically healthy overweight/obesity, latent (normal associated metabolic disorders, most importantly - insulin resistance adipocytokines imbalance). Ob...