BACKGROUND Accelerated telomere shortening may cause cancer via chromosomal instability, making it a potentially useful biomarker. However, publications on blood telomere length (BTL) and cancer are inconsistent. We prospectively examined BTL measures over time and cancer incidence. METHODS We included 792 Normative Aging Study participants with 1-4 BTL measurements from 1999 to 2012. We used...

Serum adrenal androgens (AAs), including androstenedione (Δ4A) and dehydroepiandrosterone sulfate (DHEAS), have been reported to be lower in female rheumatoid arthritis (RA) patients with early disease. Few data are available on hormonal status of women before the onset of clinical rheumatoid arthritis (pre-RA). A broad baseline panel of serum adrenal and sex steroids was compared in 36 female ...

We consider the problem of finding pre-fixed points of interactive realizers over arbitrary knowledge spaces, obtaining a relative recursive procedure. Knowledge spaces and interactive realizers are an abstract setting to represent learning processes, that can interpret non-constructive proofs. Atomic pieces of information of a knowledge space are stratified into levels, and evaluated into trut...

BACKGROUND Accumulated studies have evaluated the association of pre-miR-218 rs11134527 polymorphism with cancer risk in Chinese population. However, the results remain controversial. METHODS To derive a more precise and more comprehensive estimation of the relationship, six studies focused on Chinese population were included for the pooled analysis for pre-miR-218 rs11134527 polymorphism usi...

The commonly used linear k-ε turbulence model is shown to be incapable of accurate prediction of turbulent flows, where non-isotropy is dominant. Two examples of non-isotropic flows, which have a wide range of applications in marine waters, are saline water flow and the stratified flows due to temperature gradients. These relate to stratification and consequently, variation of density through...

Cold stratification is a requirement for seed dormancy breaking in many species, and thus it is one of the important factors for the regulation of timing of germination. However, few studies have examined the influence of various environmental conditions during cold stratification on subsequent germination, and no study has compared such effects on the performance of dormant versus non-dormant ...

AIMS To assess the benefit of off-pump coronary surgery stratified by the pre-operative risk profile. METHODS AND RESULTS Prospective and multicentric cohort study. All consecutive patients undergoing a first coronary bypass procedure between November 2001 and November 2003 were potentially eligible. Pre-operative EuroSCORE and in-hospital outcomes were prospectively collected using strictly ...

the purpose of this study was to investigate the relationship between university education and agricultural students' entrepreneurial spirit. to do this study, 150 samples were selected by using stratified random sampling methods among senior students both on graduated and undergraduates levels in bu-ali sina university. data collection tool was a researcher made questionnaire  which  its  vali...