Background. Insufficient data are available on the potential benefit of selective aspiration and clinical predictors for no-reflow in STEMI patients undergoing primary percutaneous coronary intervention (PPCI) adjunct with aspiration thrombectomy. Objective. The aim of our study was to investigate clinical predictors for insufficient reperfusion in patients with high thrombus burden treated wit...

INTRODUCTION Primary percutaneous coronary intervention (PPCI) has become the treatment of choice in patients with ST-segment elevation myocardial infarction (STEMI). Drug-eluting stents (DES) reduce restenosis compared to bare-metal stents (BMS) but there is conflicting data concerning their use in the setting of STEMI. We aimed to evaluate the influence of the type of stent on the outcomes of...

Abstract Introduction Although primary percutaneous coronary intervention (pPCI) is not a class I recommendation in all patients (pts) presenting within 12 to 48h of symptom onset (late ST-segment Elevation Myocardial Infarction, STEMI), there increasing evidence supporting its routine use this population. Data on long-term clinical outcomes sparse. Objective To evaluate MACE late-STEMI pts sub...

Correspondence to Dr Georg M Fröhlich; [email protected] In this issue of Open Heart, Hoole et al present the IMPACT trial. The authors investigate the effect of thrombus aspiration (TA) on changes in microvascular function during primary percutaneous coronary intervention (PPCI) for ST elevation myocardial infarction (STEMI). However, no difference between the TA group and the control gro...

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Recent evidence suggests that C-reactive peptide (CRP) may play an important role as a marker unstable atheromatous plaque and acute coronary syndrome (ACS). A recent retrospective study involving 102,337 ACS patients found CRP elevation resulted in significant increase short- long- term mortality. This association pr...

Abstract Funding Acknowledgements Type of funding sources: Private hospital(s). Main source(s): Jakarta Heart Center Background COVID-19 became a main health problem and causes heavy impact, especially for healthcare system. Managing ST-Segment Elevation Myocardial Infarction (STEMI) patients before pandemic was already challenging enough Healthcare Professionals (HCP) to pursue time-sensitive ...

Abstract Introduction Contrast-induced acute kidney injury (CI-AKI) is a well-known complication of ST-elevation myocardial infarction (STEMI) with an adverse impact on prognosis. Elderly patients are at higher risk for cardiovascular events. Moreover, renal function decreases age. We sought to evaluate the incidence CI-AKI in very elderly STEMI undergoing primary PCI (pPCI) and its upon outcom...

experience in a small and highly selected patient cohort with a remarkably low-risk profile and a very short time-to-treatment. There is a conflicting evidence about the prognostic significance of prodromal angina associated with pPCI, because someone found a better outcome (7), while others not (8,9). We documented that the additional infarct size reduction associated with prodromal angina tra...

Myocardial infarction (MI) remains the most common cause of heart failure (HF) worldwide. For almost 50 years HF has been recognised as a determinant of adverse prognosis after MI, but efforts to promote myocardial repair have failed to translate into clinical therapies. Primary percutaneous coronary intervention (PPCI) has driven improved early survival after MI, but its impact on the incidenc...

Abstract Objectives To compare the effects of prasugrel and ticagrelor on thrombin generation (TG) circulating endothelial progenitor cells (EPCs) in acute phase ST-segment elevation myocardial infarction (STEMI). Background TG, platelet function EPCs have an important role pathophysiology coronary artery disease (CAD). date, effect novel P2Y12 inhibitors these coagulation mediators has only be...