objective(s): to investigate the association of single nucleotide polymorphisms (snps) in the peroxisome proliferator-activated receptors gamma (pparg) with essential hypertension (eh) and additional role of gene– high-density lipoprotein cholesterol (hdl) interaction. materials and methods:a total of 1640 patients with eh (806 males, 834 females), with a mean age of 52.5±12.6 years, were selec...

KLF5 is a transcription factor. Many KLF5 target genes, such as PDGFa, PPARg, NFkB, cyclinD1, KLF4, and TCR, have been identified in different cell models. KLF5 regulates cell proliferation, cell cycle, apoptosis, and differentiation. KLF5 is an important transcription factor for cardiovascular remodeling and tumor angiogenesis. KLF5 is essential for mouse embryo development. Additionally, KLF5...