1. Muscle electrolyte (Na, K, Cl, P) concentra­ tions and fluid compartments of six children with Bartter's syndrome were compared with those of 17 control children. From four of the patients biopsies were taken twice, before and after treat­ ment with potassium chloride and spironolactone. Muscle electrolytes were determined by neutron activation in tissue sampled by needle biopsy. Results wer...

Following uephrectomy in the rat blood pressure rises while the extracellular fluid volume increases, sodium concentration falls and potassium rises. These changes (without the potassium rise) can be mimicked by simple hyperosmotic loading while the reverse can bo induced by dehydration. The rise in blood pressure is not due to either expansion of the extracellular space or the fall in sodium c...

Separated erythrocytes are washed repeatedly with iso-osmolar magnesium chloride solution, lysed by adding saponin, and sodium potassium measured in the diluted hemolysate by flame photometry. The coefficient of variation for the method was less than 4%. Reference intervals determined for a healthy population and hospitalized (elective surgery) patients without electrolyte disorders were 4.6-7....

• The mechanisms by which cardiac glycosides increase the strength of the heartbeat are far from clear.Digitalis glycosides have no major influence on cell metabolism,*" nor on the contractile proteins. At sufficiently high concentrations they interfere with the movement of ions across cell membranes and it is tempting to assume that the inotropic action of glycosides is a consequence thereof.8...

Albino rats weighing 160 to 175 gm. were fed a complete synthetic diet containing 0.003 per cent potassium and 0.7 per cent sodium for 40 days. Controls were given the same diet plus adequate added potassium. 1. Data from analyses of serum and skeletal muscle showed (a) a fall in serum chloride concentration and an increase in serum carbon dioxide concentration and pH in the potassium-deficient...

introduction: many of those who survive following an earthquake die in the next phase due to preventable and treatable medical conditions such as hyperkalemia. the present study aimed to evaluate the trend of potassium changes in crush syndrome patients of bam earthquake. methods: in this retrospective cross-sectional study, using the database of bam earthquake victims, which were developed by ...

Objectives: To compare serum potassium concentrations in diabetic and non-diabetic patients in the early phase of acute coronary syndromes. Background: Acute phase hypokalaemia occurs in response to adrenergic activation, which stimulates membrane bound sodium-potassium-ATPase and drives potassium into the cells. It is not known whether the hypokalaemia is attenuated in patients with diabetes b...

BACKGROUND It has been suggested that potassium concentrations may vary between different geographical regions, possibly reflecting ethnic differences in potassium status. This study compared the serum potassium concentrations of three Asian ethnicities in a single geographical location. METHODS Details of simultaneous serum potassium, creatinine, cholesterol, triglyceride and serum index mea...

The effect of a high external potassium concentration on the synthesis and deposition of matrix components by chondrocytes in cell culture was determined. There is a twofold increase in the amount of chondroitin 4- and 6-sulfate accumulated by chondrocytes grown in medium containing a high potassium concentration. There is also a comparable increase in the production of other sulfated glycosami...

BACKGROUND Acetaminophen overdose may be accompanied by electrolyte disturbances. The basis for electrolyte change appears to be due to increased fractional urinary electrolyte excretion. PURPOSE This study investigated the impact of serum acetaminophen concentration on changes in serum potassium, creatinine and urea concentrations in patients with acetaminophen overdose. METHODS This was a...