background: knowledge of the magnitude of avoidable burden by risk factors is needed for health policy, priority setting, and preventing stroke. the aim of this study was to estimate the contribution of selected risk factors including hypertension, overweight, obesity, tobacco use, and physical inactivity to the attributable burden of stroke in iran. methods: the world health organization compa...

The recent large genotyping studies have identified a new repertoire of disease susceptibility loci of unknown function, characterized by high allele frequencies and low relative risks, lending support to the common disease-common variant (CDCV) hypothesis. The variants explain a much larger proportion of the disease etiology, measured by the population attributable fraction, than of the famili...

The prevalence ofStreptococcus pneumoniae (pneumococcus) carriage is higher in adults who are infected with human immunodeficiency virus (HIV) than in adults who are not. We hypothesized that infants exposed to HIV become carriers of nasopharyngeal pneumococcus earlier and more frequently than infants who are not exposed to HIV. We compared infant pneumococcal acquisition by maternal HIV status...

A sudden increase in the incidence of scrapie in Italy in 1997 was subsequently linked to the use of a potentially infected vaccine against contagious agalactia. The relative risk for the exposed farms ranged between 6 and 40. The aim of this study was to assess the long-term impact of exposure to the potentially scrapie-contaminated vaccine on the Italian classical scrapie epidemic. We carried...

Scenarios can be defined as alternative versions of the same dataset, with the same variables but different observations and/or values. Applied scientists frequently want to predict how much good an intervention will do, by comparing outcomes from the same model betwen different scenarios. Alternatively, they may want to compare outcomes between different models applied to the same scenario, as...

Introduction: There is evidence that malnutrition during the first 1000 days of life contributes to the development of chronic diseases in adulthood and therefore may produce a lasting impact on the health of the population. Colombia, like other middle-income countries suffers the double burden of malnutrition in pregnant women and children under 5 years. Also, chronic diseases have positioned ...

OBJECTIVE To examine the fraction of long-term sickness absence periods attributable to physical and psychosocial work environmental risk factors. METHOD A random population sample was followed for 18 months in a national register of social transfer payments. Mutually adjusted hazard ratios for onset of long-term sickness absence and aetiological fractions were computed. RESULTS After mutua...

The prevalence of Streptococcus pneumoniae (pneumococcus) carriage is higher in adults who are infected with human immunodeficiency virus (HIV) than in adults who are not. We hypothesized that infants exposed to HIV become carriers of nasopharyngeal pneumococcus earlier and more frequently than infants who are not exposed to HIV. We compared infant pneumococcal acquisition by maternal HIV statu...