BACKGROUND AND PURPOSE The computed tomography angiography (CTA) spot sign is a validated predictor of hematoma expansion and poor outcome in supratentorial intracerebral hemorrhage (ICH), but patients with brainstem ICH have typically been excluded from the analyses. We investigated the frequency of spot sign and its relationship with hematoma expansion and outcome in patients with primary pon...

Background and Purpose Etiology and symptomatology in pontine infarction extending to the basal surface are supposed to be different from those in deep pontine infarction of the lacunar type. The aim of this study was to compare the infarct size and location, vascular lesions, risk factors, and neurological deficits in three different types of acute pontine infarction. Methods We studied isolat...

We present three cases that we suggest require a novel diagnosis and a reconsideration of current understandings of pontine anatomy. In this case series, we highlight a series of patients with monophasic, fully recovering inflammatory lesions in the pontine tegmentum not due to any of the currently recognized causes of this syndrome. We highlight other similar cases in the literature and sugges...

A 58-year-old woman presented with subacute onset of tetraparesis, anarthria, and dysphagia after rapid correction of hyponatremia caused by repeated vomiting. Brain MRI showed pontine and extrapontine lesions typical for the osmotic demyelination syndrome (figure, A and B). The pontine lesion showed nonhomogeneous contrast enhancement (figure, C), which diminished after 15 days (figure, D). Ba...

We report central pontine myelinolysis in orthotopic liver transplant patients. Sequential MR imaging of these patients with central pontine myelinolysis shows progressive decrease of T2-weighted MR signal in the pons, which may not resolve despite complete neurologic recovery.

Five groups of rats were trained in an active avoidance task in a shuttle box with different conditioned stimuli. Animals with either a light-conditioned stimulus or with electrical stimulation of the ventral pontine nucleus as a conditioned stimulus rapidly learned to avoid an aversive event, while those with no conditioned stimulus, with electrical stimulation of the lateral pontine nucleus o...

Bleeding Is the Major Cause of Death After Subarachnoid Hemorrhage • Trial of Nimodipine in Acute Ischemic Hemispheric Stroke • Arterial Enlargement in the Atherosclerosis Risk in Communities (ARIC) Cohort • Prognosis of Young Adults With Ischemic Stroke • Interconversion of Stroke Scales: Implications for Therapeutic Trials • Comparison of Clinical and Neuroradiological Findings in First Strok...

Introduction: The occurrence of subarachnoid hemorrhage (SAH) in traumatic brain injury (TBI) is 12% ~ 53% and related to poor outcome (1, 2). Early diagnosis of SAH and active intervention in removing hemorrhage from subarachnoid space is of great significance in the management of acuteTBI. Susceptibility weighted imaging (SWI) has been successfully applied in TBI and proved to be 6 times more...