A single polyp of the large intestine is a well recognized entity. It is found in both children and adults and is to be differentiated from familial adenomatosis of the large intestine, which has been fully reviewed by Lockhart-Mummery and Dukes (1939). The presenting symptom in most cases is rectal bleeding which may be of a chronic nature or may be severe. Other symptoms are prolapse of the p...

Colorectal polyp may be defined as growth of tissue on the lining of colon and rectum. It is assumed that adenomatous polyp is the most potent precursor of colorectal cancer [1]. Consequently colonoscopic polypectomy can reduce risk of colorectal cancer [2]. All polyps are not cancerous nonetheless large number of colon cancers grow as a consequence of adenomatous polyp [3]. Though colorectal c...

Synthetic polyp generation is a good alternative to overcome the privacy problem of medical data and lack various samples. In this study, we propose deep learning-based image framework that generates synthetic images are similar real ones. We suggest converts given into negative (image without polyp) using simple conditional GAN architecture then new-looking same network. addition, by controlla...

BACKGROUND There are sparse data on genetic, epigenetic and vitamin D exposure in African Americans (AA) with colon polyp. Consequently, we evaluated serum 25(OH) D levels, vitamin D receptor (VDR) polymorphisms and the methylation status of the tumor suppressor gene dickkopf homolog 1 (DKK1) as risk factors for colon polyp in this population. METHODS The case-control study consisted of 93 pa...

colonoscopy, in which a pedunculated polyp, 4 cm × 2.8 cm in size with a 2.5-cm wide flat stalk, was identified in the sigmoid colon (●" Fig. 1). For the safe and complete resection of the polyp, prophylactic endoclips (Hx-600–135; Olympus, Hachioji-shi, Tokyo, Japan) were applied to both sides of the stalk but appeared to be ineffective (●" Fig. 2). We then applied a detachable endoloop (MAJ-2...

BACKGROUND Obesity increases the risk of colon cancer. It is also known that most colorectal cancers develop from adenomatous polyps. However, the effects of obesity and adipokines on colonic polyp formation are unknown. METHODS To determine if BMI, waist circumference or adipokines are associated with colon polyps in males, 126 asymptomatic men (48-65 yr) were recruited at time of colonoscop...

The physiological roles of polyphosphates (polyP) recently found in arthropod mitochondria remain obscure. Here, the relationship between the mitochondrial membrane exopolyphosphatase (PPX) and the energy metabolism of hard tick Rhipicephalus microplus embryos are investigated. Mitochondrial respiration was activated by adenosine diphosphate using polyP as the only source of inorganic phosphate...

Prospective investigation has been undertaken with the aim to study the frequency, location and age and sex distribution of various histological types of benign gastric epithelial polyps. Histological type--adenomatous, hyperplastic and fundic gland polyps--was diagnosed on the basis of at least three histological samples taken from the polyp. Biopsy samples were also taken from the antrum and ...

Intestinal tumorigenesis in the ApcMin/+ model is initiated by aberrant activation of Wnt pathway. Increased IL-4 expression in human colorectal cancer tissue and growth of colon cancer cell lines implied that IL-4-induced Stat6-mediated tumorigenic signaling likely contributes to intestinal tumor progression in ApcMin/+ mice. Stat6 also appears to promote expansion of myeloid-derived suppresso...

INTRODUCTION Colorectal adenomas and other types of polyps are commonly used as end points or risk factors in epidemiologic studies. However, it is not known how accurately patients are able to self-report the presence or absence of adenomas following colonoscopy. METHODS Participants in the Colon Cancer Family Registry provided self-reports of recent colorectal cancer (CRC) screening activit...